The management of animals on our planet is being scrutinised as never before [...].
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| http://dx.doi.org/10.3390/ani13010179 | DOI Listing |
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Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis.
J Med Internet Res
January 2025
School of Journalism and Communication, Beijing Normal University, Beijing, China.
Background: Digital health interventions have emerged as promising tools to promote health behavior change and improve health outcomes. However, a comprehensive synthesis of strategies contributing to these interventions is lacking.
Objective: This study aims to (1) identify and categorize the strategies used in digital health interventions over the past 25 years; (2) explore the differences and changes in these strategies across time periods, countries, populations, delivery methods, and senders; and (3) serve as a valuable reference for future researchers and practitioners to improve the effectiveness of digital health interventions.
Mental Health Utilization Among Transgender Veterans.
JAMA Netw Open
January 2025
VA Center for Health Information and Communication, US Department of Veterans Affairs, Veterans Health Administration, Health Systems Research CIN 13-416, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana.
Importance: Compared with cisgender (CG) individuals, transgender and gender-diverse (TGD) individuals experience substantial social and economic disparities that can result in adverse mental health consequences. It is critical to understand potential barriers to care and to address the causes of the disparities in the future.
Objective: To characterize mental health care utilization among TGD veterans with depression.
Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy: A Randomized Clinical Trial With Open-Label Extension.
JAMA Neurol
January 2025
Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.
Importance: There is a lack of long-term efficacy and safety data on hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) and on RNA interference (RNAi) therapeutics in general. This study presents the longest-term data to date on patisiran for hATTR-PN.
Objective: To present the long-term efficacy and safety of patisiran in adults with hATTR-PN.
Global Prevalence of Sexual Violence Against Children: A Systematic Review and Meta-Analysis.
JAMA Pediatr
January 2025
Health Psychology Unit, Institute of Psychology, University of Klagenfurt, Klagenfurt, Austria.
Importance: Sexual violence against children is a global concern, yet worldwide figures of its prevalence are scant.
Objective: To estimate the global prevalence of sexual violence against children using national-level population-based studies.
Data Sources: We searched the PubMed, Embase, CINAHL, Web of Science, PsycINFO, ERIC, and APA PsycArticles databases from their respective inceptions to March 2022.
Innovations in RNA therapeutics: a review of recent advances and emerging technologies.
Nucleosides Nucleotides Nucleic Acids
January 2025
Faculty of Agriculture and Allied Sciences, C.V. Raman Global University, Bhubaneswar, India.
The field of biomedical science has witnessed another milestone with the advent of RNA-based therapeutics. This review explores three major RNA molecules, namely: messenger RNA (mRNA), RNA interference technology (RNAi), and Antisense Oligonucleotide (ASO), and analyses U.S.
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