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The acute effect of high-dose supplemental oxygen on haemodynamics assessed by echocardiography in patients with pulmonary vascular disease living in Quito at 2850 m: a randomized, single-blind, placebo-controlled crossover trial.
Eur Heart J Open
November 2024
Department of Pulmonology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.
Aims: More than 220 Mio people live at altitudes above 2000 m, many of whom have pre-existing chronic diseases, including pulmonary vascular diseases (PVDs) such as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). We investigated the acute effects of high-dose supplemental oxygen on pulmonary haemodynamics assessed by echocardiography in patients with PVD permanently living at 2850 m.
Methods And Results: In a randomized, single-blind, placebo-controlled crossover trial, patients with PVD diagnosed with PAH or CTEPH were allocated to receive 10 L/min supplemental oxygen (FiO ≈ 95%) and placebo air administered via a facial mask with reservoir near their living altitude in Quito at 2850 m (FiO0.
The Prognostic Value of Right Ventricular Dysfunction in Dilated Cardiomyopathy: Superiority of 3D Right Ventricular Ejection Fraction over Conventional Parameters and over Right Ventriculo-Arterial Coupling.
J Am Soc Echocardiogr
December 2024
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; Emergency Clinical Hospital, Bucharest, Romania.
Critical Care Ultrasound in Shock: A Comprehensive Review of Ultrasound Protocol for Hemodynamic Assessment in the Intensive Care Unit.
J Clin Med
September 2024
Critical and Intensive Care Medicine Department, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá 110111, Colombia.
Article Synopsis
- Shock is a critical condition that can lead to organ failure if not recognized and treated quickly, especially in the ICU where it's frequently seen.
- A review introduces an ultrasound-based protocol to assess hemodynamics in shock, categorizing it by cardiac index and identifying its different causes like obstructive, hypovolemic, cardiogenic, and distributive shock.
- Utilizing critical care ultrasound helps clinicians not only diagnose the type of shock but also tailor the treatment effectively while monitoring patient progress, improving overall outcomes.
Science of left ventricular unloading.
Perfusion
July 2024
Cardiothoracic and Vascular Anesthesia and Intensive Care, Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
The concept of left ventricular unloading has its foundation in heart physiology. In fact, the left ventricular mechanics and energetics represent the cornerstone of this approach. The novel sophisticated therapies for acute heart failure, particularly mechanical circulatory supports, strongly impact on the mechanical functioning and energy consuption of the heart, ultimately affecting left ventricle loading.
View Article and Find Full Text PDFVentriculo-arterial (VA) coupling and fQRS as new selection criteria for primary prevention ICD placement.
Intensive Care Med Exp
July 2024
Heart, Sepsis and Trauma Research Laboratory, College of Medicine & Dentistry, James Cook University, 1 James Cook Drive, Townsville, QLD, 4811, Australia.
For decades, left ventricular ejection fraction (LVEF < 35%) has been a mainstay for identifying heart failure (HF) patients most likely to benefit from an implantable cardioverter defibrillator (ICD). However, LVEF is a poor predictor of sudden cardiac death (SCD) and ignores 50% of HF patients with mildly reduced and preserved LVEF. The current international guidelines for primary prophylaxis ICD therapy are inadequate.
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