AI Article Synopsis
- - The study sequenced the whole genome of mulberry crinivirus (MuCV), a new type of virus affecting mulberry plants, revealing it has a bipartite genome with two RNA segments.
- - RNA1 is 8571 nucleotides long and contains four open reading frames (ORFs), including one that encodes a polyprotein with various important functional domains.
- - RNA2, which is 8082 nucleotides long, has eight ORFs similar to those found in other criniviruses; phylogenetic analysis suggests MuCV is part of group 1 of this viral family.
Article Abstract
The whole genome sequence of mulberry crinivirus (MuCV), a novel member of the genus Crinivirus (family Closteroviridae) identified in mulberry (Morus alba L), was determined. The virus possesses a bipartite genome. RNA1 contains 8571 nucleotides (nt) with four open reading frames (ORFs). ORF1a encodes a putative polyprotein with papain-like protease, methyltransferase, and RNA helicase domains. ORF1b putatively encodes an RNA-dependent RNA polymerase (RdRp), which is probably expressed via a + 1 ribosomal frameshift. RNA2 consists of 8082 nt, containing eight ORFs that are similar in size and position to orthologous genes of other criniviruses. Phylogenetic analysis based on RdRp amino acid sequences of criniviruses placed MuCV in group 1.
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| http://dx.doi.org/10.1007/s00705-022-05657-7 | DOI Listing |
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