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Clarifying the grey space of sugammadex induced bradycardia.
Curr Opin Anaesthesiol
August 2023
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Purpose Of Review: This review describes recent prospective and retrospective work exploring the incidence and clinical consequence of sugammadex-induced bradycardia and an update of recent evidence and adverse event reports to the United States Food and Drug Administration regarding the incidence of sugammadex induced bradycardia.
Recent Findings: This work suggests that the incidence of sugammadex-induced bradycardia can range from 1 to 7% depending on the definition to reverse moderate to deep neuromuscular blockade. For most instances, the bradycardia is inconsequential.
Article Synopsis
- A 68-year-old man experienced severe bradycardia and cardiac arrest after undergoing surgery with rocuronium and receiving sugammadex for muscle relaxation reversal.
- Despite initial treatment not working, he was successfully resuscitated after 4 minutes, remained stable, and was discharged without issues.
- The case highlights a potential complication of sugammadex that has been noted before, calling for increased awareness among medical professionals.
Sugammadex induced bradycardia and hypotension: A case report and literature review.
Medicine (Baltimore)
July 2021
Department of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Rationale: There is evidence that sugammadex can facilitate extubation post-surgery and attenuate postoperative pulmonary complications resulting from postoperative residual neuromuscular blockade. However, it may induce adverse effects, including bronchospasm, laryngospasm, bradycardia, hypotension, and cardiac arrest. Here, we present a case of sugammadex-induced bradycardia and hypotension.
View Article and Find Full Text PDFSugammadex-induced atropine-resistant bradycardia: clinical, pathophysiologic, and electrocardiographic considerations.
JA Clin Rep
May 2020
Department of Cardiology, University of Patras Medical School, Queen Olgas Square, 7 Aratou Street, 26221, Patras, Greece.
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