Population subdivision among several neotropical malaria vectors has been widely evaluated; however, few studies have analyzed population variation at a microgeographic scale, wherein local environmental variables may lead to population differentiation. The aim of the present study was to evaluate the genetic and geometric morphometric structure of Anopheles nuneztovari and Anopheles albimanus in endemic localities of northwestern Colombia. Genetic and phenetic structures were evaluated using microsatellites markers and wing geometric morphometrics, respectively. In addition, entomological indices of importance in transmission were calculated. Results showed that the main biting peaks of Anopheles nuneztovari were between 20:00 and 22:00, whereas Anopheles albimanus exhibited more variation in biting times among localities. Infection in An. nuneztovari by Plasmodium spp. (IR: 4.35%) and the annual entomological inoculation rate (30.31), indicated high vector exposure and local transmission risk. We did not detect Plasmodium-infected An. albimanus in this study. In general, low genetic and phenetic subdivision among the populations of both vectors was detected using a combination of phenotypic, genetic and environmental data. The results indicated high regional gene flow, although local environmental characteristics may be influencing the wing conformation differentiation and behavioral variation observed in An. albimanus. Furthermore, the population subdivision detected by microsatellite markers for both species by Bayesian genetic analysis provides a more accurate picture of the current genetic structure in comparison to previous studies. Finally, the biting behavior variation observed for both vectors among localities suggests the need for continuous malaria vector surveys covering the endemic region to implement the most effective integrated local control interventions.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821454 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0280066 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Malaria Vectors and Transmission in Malaria-Endemic Localities of Colombia.
Trop Med Infect Dis
November 2024
Grupo Microbiología Molecular, Escuela de Microbiología, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.
species composition, abundance, and natural infection are important aspects to assess malaria transmission risk. In this study, these aspects were evaluated in a large number of localities in the most important malaria-endemic regions of Colombia. Mosquitoes were collected from 2012 to 2015 in 55 localities of northwestern and western Colombia.
View Article and Find Full Text PDFMechanism of complement inhibition by a mosquito protein revealed through cryo-EM.
Commun Biol
May 2024
NIH-NIAID, Laboratory of Malaria and Vector Research, Rockville, MD, USA.
Salivary complement inhibitors occur in many of the blood feeding arthropod species responsible for transmission of pathogens. During feeding, these inhibitors prevent the production of proinflammatory anaphylatoxins, which may interfere with feeding, and limit formation of the membrane attack complex which could damage arthropod gut tissues. Salivary inhibitors are, in many cases, novel proteins which may be pharmaceutically useful or display unusual mechanisms that could be exploited pharmaceutically.
View Article and Find Full Text PDFInsecticide susceptibility status of Anopheles albimanus populations in historical malaria foci in Quintana Roo, Mexico.
Malar J
May 2024
Unidad Colaborativa de Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, Yucatán, Mexico.
Article Synopsis
- Mexico has significantly reduced malaria cases over the last 20 years and is considering certifying malaria-free areas (MFAs) as a step towards total elimination, with Quintana Roo being a potential candidate.
- Monitoring the susceptibility of key malaria vectors like Anopheles albimanus is essential for this MFA certification, leading to a study conducted in three localities in Quintana Roo during the rainy season of 2022.
- The study found that An. albimanus showed high mortality rates against various insecticides, and genetic analysis revealed no mutations in key resistance genes, indicating that the vector population remains susceptible.
Chemical control of medically important arthropods in Panama: A systematic literature review of historical efforts.
Acta Trop
July 2024
Programa Centroamericano de Maestría en Entomología, Vicerrectoría de Investigación y Postgrado, Universidad de Panamá, República de Panamá; Smithsonian Tropical Research Institute, Panama City, Panama; Instituto de Investigaciones Científicas & Servicios de Alta Tecnología, Edificio 219, Clayton, PO 0843-01103, Ciudad del Saber, República de Panamá. Electronic address:
Vector-borne diseases are a major source of morbidity in Panama. Herein, we describe historical usage patterns of synthetic insecticides to control arthropod disease vectors in this country. We examine the influence of interventions by vector control programs on the emergence of insecticide resistance.
View Article and Find Full Text PDFPhenotypic resistance not associated with knockdown mutations (kdr) in Anopheles albimanus exposed to deltamethrin in southern coastal Ecuador.
Malar J
January 2024
Centro de Investigación para la Salud en América Latina, Pontificia Universidad Católica del Ecuador, Calle Pambacienda y San Pedro del Valle, Campus Nayón, 170530, Nayón, Ecuador.
Background: Decrease in malaria rates (e.g. incidence and cases) in Latin America maintains this region on track to achieve the goal of elimination.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!