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Should Low-Risk Pregnant Patients be Screened for Asymptomatic Bacteriuria?
NEJM Evid
February 2025
Department of Microbiology, Sinai Health and University Health Network, Toronto.
AbstractScreening and treatment of asymptomatic bacteriuria is generally not recommended due to a lack of clinical benefit and potential harm. A notable exception is the recommendation for routine screening during pregnancy. In this Tomorrow's Trial, the authors review the relevant evidence and propose a trial to address the question, "should low-risk pregnant patients be screened for asymptomatic bacteriuria?"
View Article and Find Full Text PDFThe circulating plasma microRNA signature in human visceral leishmaniasis.
mSphere
January 2025
Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Visceral leishmaniasis (VL) is a vector-borne disease caused by the obligate intracellular protozoan in India. VL can be complicated by post-kala-azar dermal leishmaniasis (PKDL), a macular or nodular rash that develops in 10%-20% of patients after treatment of VL in India. Patients with PKDL are infectious to sand flies, promoting further transmission of the parasite.
View Article and Find Full Text PDFBackground: Babesiosis poses significant risks of adverse outcomes in individuals with immunocompromising conditions (IC) and asplenia/hyposplenia (AH). This study compares clinical outcomes between these vulnerable groups and immunocompetent patients.
Methods: A multicenter retrospective cohort study included adult patients with laboratory-confirmed babesiosis from 2009 to 2023.
A scientometric study of syphilis research by dermatologists and stomatologists: Underpinning their roles in public health.
J Dent Sci
January 2025
Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/purpose: launched a call to action for dermatologists in the rise of syphilis. In practice, dermatologists and stomatologists perform early diagnoses of syphilis and refer patients to adequate treatment.
Materials And Methods: This scientometric study aimed to investigate and compare research trends and characteristics of syphilis publications by dermatologists and stomatologists in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
Risk Factors of Hemophagocytic Lymphohistiocytosis in Adults with Fever of Unknown Origin: A Retrospective Study.
Int J Gen Med
January 2025
Department of Infectious Diseases, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Purpose: Hemophagocytic lymphohistiocytosis (HLH) is a critical syndrome with a high mortality rate. In clinical practice, some patients with fever of unknown origin (FUO) can develop HLH, further complicating the diagnosis and treatment. However, studies on HLH in adults with FUO are limited.
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