Neuronal populations were estimated in the ganglion cell layer (GCL) of the adult hamster retina. The total number of neurones averaged 128,000 in Nissl-stained whole-mounts. Following injections of horseradish peroxidase into the brain, an average of 72,000 cells were labeled (mostly above 8 micron in diameter), indicating that 56% of the neurones in the GCL are ganglion cells. Forty-one percent of the neurones (mostly below 8 micron diameter) of the GCL survived for 5 months after optic nerve transection at 12 days after birth. The results indicate that more than 40% of the neurones in the GCL of the hamster retina are displaced amacrine cells.
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