AI Article Synopsis
- The study examined the effects of the TopClosure tension-relief system (TRS) on breast cancer patients undergoing mastectomy.
- A total of 402 female patients were divided into a TRS group and a control group, with various health markers measured pre- and post-surgery.
- Results showed that TRS reduced complications like flap necrosis and infection, improved inflammation levels, scar outcomes, and overall quality of life.
Article Abstract
The present randomized controlled study aimed to investigate the effects of TopClosure tension-relief system (TRS) on patients with breast cancer undergoing mastectomy. A total of 402 female patients with breast cancer who came to the Renmin Hospital of Wuhan University between March 2014 and June 2018 were involved in the present study. All patients receiving mastectomy were randomly divided into the TRS group (n=201) and the control group (n=201). Serum levels of high-sensitivity C-reactive protein, TNF-α, IL-6 and procalcitonin were measured using ELISA. Vancouver Scar Scale was recorded at 2 weeks and 1-3 and 6 months following the operation. The 36-Item Health Survey Scales were performed for all patients at 1 month after surgery. The TRS reduced the incidence of flap necrosis, infection and the duration of hospital stay. In addition, the TRS was found to attenuate inflammation and improve scar outcomes as well as the quality of life. It was concluded that the TRS could significantly improve the clinical outcomes.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798149 | PMC |
| http://dx.doi.org/10.3892/etm.2022.11769 | DOI Listing |
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