Right frontal EEG asymmetry has been a commonly neurophysiological marker of anxiety and depressive symptoms throughout development. In the current study, EEG asymmetry measures in frontal and parietal regions were examined as markers for specific subtypes of childhood anxiety disorder (eg, panic, generalized, social, separation, and school avoidance). Notably, panic trait levels were significantly associated with prefrontal and lateral frontal alpha asymmetry, general anxiety was predicted by parietal beta asymmetry measures, and social anxiety levels were associated with mid-frontal alpha and beta asymmetry. School avoidance was significantly correlated with prefrontal and lateral frontal beta asymmetry scores; however, no significant findings were detected relating to separation anxiety which is considered unique to childhood anxiety. In all cases, increased anxiety subtype scores related to a rightward shift in asymmetry, signifying this trait as a key neurophysiological marker of childhood anxiety symptoms. Overall, biomarker research of specific subtypes of broad conditions like anxiety could be highly useful for facilitating a deeper understanding of the mechanisms involved, as well as customizing treatment approaches.
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http://dx.doi.org/10.1177/15500594221150213 | DOI Listing |
BMC Pregnancy Childbirth
January 2025
REALIFE Research Group, Women and Child, Department of Development and Regeneration, KU Leuven, Louvain, 3000, Belgium.
Aim: To understand the extent and type of evidence in relation to the effectiveness of intervention strategies targeting working pregnant women, and their partners, for the prevention of mental health problems (depression, anxiety) and improving resilience, from conception until the child is 5 years of age.
Methods: A scoping review was conducted searching Pubmed (including Medline), Embase, Web of Science Core Collection and Scopus. Inclusion criteria were based on population (employed parents), context (from -9 months to 5 years postpartum) and concept (mental health problems, resilience and prevention/ preventative interventions).
J Psychosom Res
January 2025
Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland. Electronic address:
Objective: Previous studies implied detrimental effects of adverse childhood experiences (ACE) on cardiovascular disease and mental health. Still, data on the influence of ACE on psychological distress in patients with an implantable cardioverter-defibrillator (ICD) are lacking.
Methods: We prospectively recruited 423 patients with an ICD.
Psychol Trauma
January 2025
Department of Psychiatry, First Affiliated Hospital of Jinan University.
Objective: Eye movement desensitization and reprocessing therapy (EMDR) is effective in treating major depressive disorder (MDD) with childhood trauma, and virtual reality (VR) can further extend its application form. However, the utilization of VR-EMDR in treating MDD with childhood trauma is still in its infancy, and whether it can improve depressive symptoms and traumatic experience remains unknown.
Method: Seventy-two MDD patients were randomly allocated to the intervention group and the wait-list control group on a 1:1 basis.
Background: People with Down syndrome (DS) are genetically at-risk for Alzheimer's disease (AD). The age of symptomatic AD in DS varies (late-40s-70s). Lifestyle factors are theorized to explain some of this variability.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Lab of Neuropsychology & Behavioral Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Background: Prior longitudinal studies have found that individuals born during World War II and the postwar period had lower incident dementia (Tom et al., 2020) than previous generations, a finding contradictory to research indicating early-life stressors as adverse events for late-life cognition. This study aimed to further explore this association and underlying factors.
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