AI Article Synopsis
- Inflammation from eosinophilic esophagitis (EoE) can cause esophageal strictures, making it difficult to assess esophageal narrowing in patients.
- This study compared esophageal distensibility in adults with EoE to those without, revealing that EoE patients had notably lower distensibility.
- The findings suggest that current methods for assessing fibrostenosis may not be sufficient, as some patients had narrow esophagi without displaying typical symptoms, highlighting the value of impedance planimetry for better diagnosis.
Article Abstract
Introduction: Inflammation in eosinophilic esophagitis (EoE) often leads to esophageal strictures. Evaluating esophageal narrowing is clinically challenging. We evaluated esophageal distensibility as related to disease activity, fibrosis, and dysphagia.
Methods: Adult patients with and without EoE underwent endoscopy and distensibility measurements. Histology, distensibility, and symptoms were analyzed.
Results: Patients with EoE had significantly lower distensibilities than controls. We found a cohort with esophageal diameter under 15 mm despite lack of dysphagia.
Discussion: This study raises concern that current assessments of fibrostenosis are suboptimal. We describe a cohort with unrecognized slender esophagus that were identified through impedance planimetry measurements. This tool provides additional information beyond symptomatic, histologic, and endoscopic assessments.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132706 | PMC |
| http://dx.doi.org/10.14309/ctg.0000000000000564 | DOI Listing |
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