AI Article Synopsis
- The study investigated risk factors for Low Cardiac Output Syndrome (LCOS) in patients who underwent pericardiectomy at three hospitals over a 27-year period.
- Out of 826 patients, 126 experienced LCOS, indicating a 15.3% postoperative incidence, along with a noted 8% operative mortality rate.
- Key risk factors for LCOS identified include postoperative and preoperative left ventricular end-diastolic diameter, surgical delay, pericardium thickness, intubation duration, fluid management, and complications such as tuberculosis pericarditis.
Article Abstract
Background: We aimed to investigate risk factors of LCOS following pericardiectomy.
Methods: This was a retrospective study of patients undergoing pericardiectomy at three hospitals between January 1994 and May 2021.
Results: A total of 826 patients were divided into two groups: group with LCOS (N = 126) and group without LCOS (N = 700). The incidence of postoperative LCOS was 15.3%. There were 66 operative deaths (8.0%). Univariable and multivariable analyses showed that factors are associated with LCOS, including postoperative LVEDD (P < 0.001), preoperative LVEDD (P < 0.001), time between symptoms and surgery (P < 0.001), thickness of pericardium (P < 0.001), intubation time (P = 0.002), hospitalized time postoperative (P < 0.001), preoperative central venous pressure (P = 0.016), postoperative central venous pressure (P = 0.034), D0 fluid balance (P = 0.019), D2 fluid balance (P = 0.017), postoperative chest drainage (P < 0.001), surgical duration (P < 0.001), bleeding during operation (P = 0.001), serum creatinine 24h after surgery (P < 0.001), serum creatinine 48h after surgery (P = 0.017), fresh-frozen plasma (P = 0.005), packed red cells (P = 0.006), and tuberculosis pericarditis (P = 0.026).
Conclusion: In our study, incomplete pericardial dissection, fluid overload, delayed diagnosis and treatment, and tuberculosis pericarditis are associated with LCOS following pericardiectomy.
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| http://dx.doi.org/10.1532/hsf.4449 | DOI Listing |
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