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Induced Chirality in QDs Using Thermoresponsive Elastin-like Polypeptides.
Langmuir
December 2024
Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Circular dichroism (CD) spectroscopy has emerged as a potent tool for probing chiral small-molecule ligand exchange on natively achiral quantum dots (QDs). In this study, we report a novel approach to identifying QD-biomolecule interactions by inducing chirality in CdS QDs using thermoresponsive elastin-like polypeptides (ELPs) engineered with C-terminal cysteine residues. Our method is based on a versatile two-step ligand exchange process starting from monodisperse oleate-capped QDs in nonpolar media and proceeding through an easily accessed achiral glycine-capped QD intermediate.
View Article and Find Full Text PDFPrevalence and Influencing Factors of Tobacco Use Among Physicians in Madinah City, Saudi Arabia, in 2024.
Cureus
November 2024
Internal Medicine, King Salman Bin Abdulaziz Medical City, Madinah, SAU.
Background Smoking is recognized as a major public health issue globally; it is widely distributed among people of various origins and races in the world despite hard efforts on cessation programs. Its health hazards extend to dangerous complications, which mostly end in death according to statistics around the world. Tobacco use is influenced by several factors, which may include social pressures from peers, family influences, and media portrayals of smoking.
View Article and Find Full Text PDFGeographic variation in modern contraceptive utilization among women of reproductive age in Mozambique: a multilevel analysis.
Contracept Reprod Med
December 2024
Department of Human Physiology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Background: Modern contraceptives are crucial for reducing maternal and child mortality, yet Mozambique's contraceptive prevalence rate is very low, with significant regional disparities. This study investigates geographic variation in contraceptive use and the individual, community, and regional factors influencing it to guide equitable family planning interventions.
Methods: This study utilized data from the 2022/23 Mozambique Demographic and Health Survey, analyzing a weighted sample of 9,316 women aged 15-49.
Fatigue, pain and faecal incontinence in adult inflammatory bowel disease patients and the unmet need: a national cross-sectional survey.
BMC Gastroenterol
December 2024
Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, 57 Waterloo Road, London, London, SE1 8WA, UK.
Background And Aims: The co-existence of fatigue, pain and faecal incontinence in people with Inflammatory Bowel Disease (IBD) is unknown. We aimed to determine the presence of and relationship between these symptoms and patients' desire for intervention.
Methods: Adults with IBD in the UK, recruited from clinics, the national IBD-BioResource, a patient charity and social media sources, completed PROMIS validated patient-reported questionnaires to identify fatigue, pain and faecal incontinence, in addition to symptom severity and impact, disease activity, anxiety and depression questionnaires and questions about their desire for help with these symptoms.
Public perceptions of digital mental health awareness campaign in the Arab Gulf states: a qualitative thematic analysis.
Front Public Health
December 2024
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Mental illness is a significant public health concern and a leading cause of disability worldwide. Research shows a lack of mental health knowledge and inappropriate practices in the Gulf Cooperation Council (GCC) states. Our study aimed to evaluate individuals' perspectives on mental health by analyzing their responses to a digital campaign directed at GCC adolescents.
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