The report of the Executive Committee for 2021 is presented.
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Immunohistochemical Expression of PAX8 in Central Nervous System Hemangioblastomas: A Potential Diagnostic Pitfall for Neuropathologists.
Appl Immunohistochem Mol Morphol
January 2025
Department of Medical and Surgical Sciences and Advanced Technologies "G.F. Ingrassia," Anatomic Pathology, University of Catania.
The histologic differential diagnosis between intracranial hemangioblastoma (HB) and metastatic clear cell renal cell carcinoma may be challenging, especially considering that both tumors exhibit clear cell morphology and can be associated with vHL mutation and/or Von Hippel-Lindau syndrome. As the execution of immunohistochemical analyses is often mandatory, the expression of PAX8 has been traditionally considered a reliable marker of metastatic clear cell renal cell carcinoma, being consistently negative in intracranial HB. However, as in recent years, some cases of PAX8-positive HBs have been reported in the literature; we studied the expression of this antibody on a series of 23 intracranial HB, showing that about 40% of these tumors may express PAX8 and that this immunoreactivity is often focal and weak.
View Article and Find Full Text PDFAssociations of high-sensitivity C-reactive protein with neuropsychological outcomes and cerebral white matter hyperintensities in older adults at risk of dementia.
Brain Behav Immun Health
February 2025
Healthy Brain Ageing Program, Brain and Mind Centre, School of Psychology, Faculty of Science, University of Sydney, NSW, 2050, Australia.
Inflammation is becoming increasingly recognised as a core feature of dementia with evidence indicating that its role may vary and adapt across different stages of the neurodegenerative process. This study aimed to investigate whether the associations of high-sensitivity C-reactive protein (hs-CRP) with neuropsychological performance (verbal memory, executive function, processing speed) and cerebral white matter hyperintensities (WMHs) differed between older adults with subjective cognitive decline (SCD; = 179) and mild cognitive impairment (MCI; = 286). Fasting serum hs-CRP concentrations were grouped into low (<1.
View Article and Find Full Text PDFProsocial Intentions and Subsequent Cognitive Health: A Prospective Cohort Study.
J Gerontol B Psychol Sci Soc Sci
January 2025
Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Objectives: Prosociality, defined as positive other-regarding intentions and behaviors, is a modifiable factor demonstrated to be associated with better mental, physical, and cognitive health in older adults. Prior studies have largely focused on individual prosocial behaviors, especially volunteering. This study examines whether prosocial intentions are associated with maintaining cognitive health over time.
View Article and Find Full Text PDFExamining sustainable hospitality practices and employee turnover in Pakistan: The interplay of robotics awareness, mutual trust, and technical skills development in the age of artificial intelligence.
J Environ Manage
January 2025
School of Business Administration (MBA School), Zhejiang Gongshang University, Hangzhou, 310018, China; Modern Business Research Center of Zhejiang Gongshang University, China. Electronic address:
Integrating robots and artificial intelligence (AI) into workplaces is becoming increasingly prevalent across various sectors, including hospitality. This trend has raised concerns regarding employee anxiety and the potential for higher turnover intentions, particularly when AI technologies are perceived to undermine professional expertise. This study explores the relationship between awareness of robotics and AI and employee turnover intentions, framed within the Conservation of Resources Theory (COR).
View Article and Find Full Text PDFEffects of high-intensity interval and moderate-intensity continuous training on ambulatory blood pressure and cardiovascular outcomes in older adults with hypertension (HEXA Study): study protocol for a randomised trial.
BMJ Open
December 2024
ExCE Research Group, Department of Physical Education, Federal University of Rio Grande do Norte, Natal, Brazil
Introduction: Approximately two-thirds of Brazilian older adults have hypertension. Aerobic training is the first-line non-pharmacological therapy for hypertension. However, the effects of different aerobic training approaches on ambulatory blood pressure in older adults are uncertain.
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