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Evaluation of an enhanced ResNet-18 classification model for rapid On-site diagnosis in respiratory cytology.
BMC Cancer
January 2025
Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China.
Objective: Rapid on-site evaluation (ROSE) of respiratory cytology specimens is a critical technique for accurate and timely diagnosis of lung cancer. However, in China, limited familiarity with the Diff-Quik staining method and a shortage of trained cytopathologists hamper utilization of ROSE. Therefore, developing an improved deep learning model to assist clinicians in promptly and accurately evaluating Diff-Quik stained cytology samples during ROSE has important clinical value.
View Article and Find Full Text PDFThe increasing availability of coarse-scale climate simulations and the need for ready-to-use high-resolution variables drive the climate community to the challenge of reducing computational resources and time for downscaling purposes. To this end, statistical downscaling is gaining interest as a potential strategy for integrating high-resolution climate information obtained through dynamical downscaling over limited years, providing a clear understanding of the gains and losses in combining dynamical and statistical downscaling. In this regard, several questions can be raised: (i) what is the performance of statistical downscaling, assuming dynamical downscaling as a reference over a shared time window; (ii) how much the performance of statistical downscaling is affected by changes in the number of years available for training; (iii) how does the climate normal considered for the training affect the predictions.
View Article and Find Full Text PDFA reduction in effective population size has not relaxed purifying selection in the human population of Eivissa (Balearic Islands).
Sci Rep
January 2025
Departament de Medicina i Ciències de la Vida, Institut de Biologia Evolutiva (CSIC-UPF), Universitat Pompeu Fabra, Dr. Aiguader 88, Barcelona, 08003, Catalonia, Spain.
Ibiza (Eivissa) is one of the main Balearic Islands in the western Mediterranean. Recent studies have highlighted the genetic distinctiveness of present-day Eivissans within the region and suggested it could be attributed to the genetic drift caused by recent demographic events. Whether this distinctiveness emerged from a differential demographic history, or rather from a bias for sampling in a small geographic region such as Eivissa, remains an open question, together with the understanding of the functional consequences of demography in the island.
View Article and Find Full Text PDFSlit Lamp Report Generation and Question Answering: Development and Validation of a Multimodal Transformer Model with Large Language Model Integration.
J Med Internet Res
December 2024
Guangzhou Cadre and Talent Health Management Center, Guangzhou, China.
Background: Large language models have shown remarkable efficacy in various medical research and clinical applications. However, their skills in medical image recognition and subsequent report generation or question answering (QA) remain limited.
Objective: We aim to finetune a multimodal, transformer-based model for generating medical reports from slit lamp images and develop a QA system using Llama2.
Thyroid surgery under nerve auto-fluorescence & artificial intelligence tissue identification software guidance.
Langenbecks Arch Surg
January 2025
Department of General Surgery, Sanatorio Otamendi & Miroli (Otamendi & Miroli Hospital), University of Buenos Aires, Buenos Aires, Argentina.
Thyroid cancer is a common malignancy that requires comprehensive clinical evaluation prior to adequate surgical management. Over the last three decades thyroid surgery has tripled and is considered one of the most commonly performed procedures in general surgery. These procedures are associated with potential postoperative complications with significant deterioration in the patient's quality of life.
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