Aim: The COVID-19 omicron variant surge highlighted the evolving impact of COVID-19. Febrile infants <60 days old are high risk for serious bacterial infections (SBI). This study evaluated the rate of SBI based on COVID-19 infection.
Methods: We conducted a retrospective chart review at an urban, academic paediatric emergency department. The study enrolled infants 60 days old or less with documented fever. The primary outcome was SBI diagnosed by blood, urine, and/or cerebrospinal fluid cultures. We compared the rate of SBI between COVID-19 groups with an omicron variant and 29- to 60-day-old subgroup analyses.
Results: Two hundred and thirty-three (233) infants meet the criteria. The incidence of SBI was 18.7% in the COVID-19 negative and 1.7% in the COVID-19-positive group which is statistically significant (p < 0.001). Omicron subgroup analysis did not achieve statistical significance (p = 0.62) while COVID-19-positive infants 29-60 days old had a statistically significant lower rate of SBI (p = 0.006).
Conclusion: The omicron variant surge provided an additional understanding of the impact of COVID-19 on these high-risk infants. These results can lead to decreased invasive testing and exposure to antibiotics as well as examine the utility of viral testing for risk stratification.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/apa.16655 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring factors influencing university students' entrepreneurial intentions: The role of attitudes, beliefs, and environmental support.
PLoS One
January 2025
School of Management, Foshan University, Foshan, China.
Entrepreneurship is an increasingly popular career choice among students, driven by the transformative impact of emerging technologies and evolving professional landscapes. This study focuses on how higher education shapes students' professional identities and entrepreneurial intentions, particularly among business school students. Utilizing the Theory of Planned Behavior (TPB) as the foundational framework, the study examines the factors influencing entrepreneurial intentions, with a specific emphasis on the moderating role of departmental identification.
View Article and Find Full Text PDFPublic Health.
Alzheimers Dement
December 2024
College of Medicine, University of Ibadan, Ibadan, Nigeria.
Background: Understanding the genetic underpinnings of Alzheimer's disease is crucial for advancing research and developing targeted interventions. Genomic research in dementia in Africa is of utmost importance based on recent reports from studies in African Americans that African ancestral gene is associated with lower risk effect for developing AD. However, dementia related genetic study is an evolving research in sub-Saharan Africa with peculiar challenges influencing participant recruitment.
View Article and Find Full Text PDFPublic Health.
Alzheimers Dement
December 2024
UNIVERSITY OF CALIFORNIA, BERKELEY, California, CA, USA; Department of Psychiatry, SRIHER, Chennai, India.
Background: Exposure to the household air pollution (HAPIN) is a leading health risk in populations in LMIC s and accounts for an estimated 2.3 million premature deaths annually and 91.5 million disability-adjusted life years (Bennitt et al,2021).
View Article and Find Full Text PDFBackground: The language symptomology associated with semantic variant primary progressive aphasia (svPPA), namely word finding difficulties with loss of word meaning, leads to multimodal communication difficulties. Given that communication plays an intricate role in establishing and sustaining relationships, svPPA can impact relationships, including those with spouses, in a manner that can only be understood by firsthand experiences. This study aimed to describe a spouse's experiences of communicating with an individual with svPPA along with the role of communication supports and expectations for speech-language therapy.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
University at Albany, SUNY, Albany, NY, USA.
Background: The experience of spouse caregivers of individuals with Alzheimer's Disease (AD) is marked by witnessing the gradual cognitive decline of their loved ones. This journey transforms the nature of their marital relationship, evolving from mutual interdependence to a more unilateral caregiving role. Despite this significant shift, the specific phenomenon of self-loss among these caregivers remains underexplored in academic research.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!