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http://dx.doi.org/10.2471/BLT.22.289501 | DOI Listing |
World J Pediatr Congenit Heart Surg
January 2025
Kirklin Solutions Inc, Birmingham, AL, USA.
Leadership in pediatric and congenital heart surgery requires a distinctive blend of clinical mastery, scientific innovation, and an unwavering commitment to education and mentorship. The individuals who rise to the top of this demanding field exhibit not only surgical prowess but also the ability to foster progress through impactful research, publications, and training the next generation of surgeons. These qualities are exemplified by the six past presidents of the (WSPCHS), whose leadership has been instrumental in advancing both the Society and the broader field of pediatric cardiac care.
View Article and Find Full Text PDFJ Environ Manage
February 2025
Indian Institute of Management Bodh Gaya (IIM Bodh Gaya), Uruvela, Prabandh Vihar, Bodh Gaya, 824234, Gaya, Bihar, India. Electronic address:
The relentless surge in carbon emissions is exacting a devastating toll on human wellbeing, critical infrastructure, and natural ecosystems, leaving a stark and distressing legacy of destruction. Communities worldwide are reeling from the impacts of pervasive smog, record-breaking wildfires, and deadly heatwaves-manifestations of a climate crisis that grows more severe by the day. Once a vanguard of environmental policy, the Organisation for Economic Co-operation and Development (OECD) now struggles with exceeding emissions targets, eroding its credibility and influence.
View Article and Find Full Text PDFBackground: LIGHT (oLaparib In HRD-Grouped Tumor types; NCT02983799) prospectively evaluated olaparib treatment in patients with platinum-sensitive relapsed ovarian cancer (PSROC) assigned to cohorts by known BRCA mutation (BRCAm) and homologous recombination deficiency (HRD) status: germline BRCAm (gBRCAm), somatic BRCAm (sBRCAm), HRD-positive non-BRCAm, and HRD-negative. At the primary analysis, olaparib treatment demonstrated activity across all cohorts, with greatest efficacy in terms of objective response rate and progression-free survival observed in the g/sBRCAm cohorts. The authors report final overall survival (OS).
View Article and Find Full Text PDFPhilos Trans R Soc Lond B Biol Sci
January 2025
Department of Zoology, University of Cambridge, Cambridge, UK.
Food production does more damage to wild species than any other sector of human activity, yet how best to limit its growing impact is greatly contested. Reviewing progress to date in interventions that encourage less damaging diets or cut food loss and waste, we conclude that both are essential but far from sufficient. In terms of production, field studies from five continents quantifying the population-level impacts of land sharing, land sparing, intermediate and mixed approaches for almost 2000 individually assessed species show that implementing high-yield farming to spare natural habitats consistently outperforms land sharing, particularly for species of highest conservation concern.
View Article and Find Full Text PDFPhilos Trans R Soc Lond B Biol Sci
January 2025
Institute of Zoology, Zoological Society of London, London NW1 4RY, UK.
The Living Planet Index (LPI) is a leading global biodiversity indicator based on vertebrate population time series. Since it was first developed over 25 years ago, the LPI has been widely used to indicate trends in biodiversity globally, primarily reported every two years in the Living Planet Report. Based on relative abundance, a sensitive metric of biodiversity change, the LPI has also been applied as a tool for informing policy and used in assessments for several multilateral conventions and agreements, including the Convention on Biological Diversity 2010 Biodiversity Target and Aichi targets.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!