Asbestos fibers interact with many different proteins and may affect either their structure or functions. The aim of this study was to determine whether ferritin absorbed onto fibers might modify its ferroxidase activity. By measuring apo-ferritin ferroxidase activity, data demonstrated that ferritin in the presence of fibers did not significantly modify this enzymatic activity. However, fibers in the absence of ferritin promoted ferrous iron oxidation. Evidence suggests that asbestos fibers may promote iron oxidation and subsequently affect cellular iron homeostatic mechanisms.
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http://dx.doi.org/10.1080/15287394.2022.2164391 | DOI Listing |
Bioinformatics
December 2024
The Kids Research Institute Australia, University of Western Australia, Nedlands, WA 6009, Australia.
Motivation: Over the last two decades, transcriptomics has become a standard technique in biomedical research. We now have large databases of RNA-seq data, accompanied by valuable metadata detailing scientific objectives and the experimental procedures employed. The metadata is crucial in understanding and replicating published studies, but so far has been underutilised in helping researchers to discover existing datasets.
View Article and Find Full Text PDFPsychooncology
January 2025
Department of Psychology, University of Turin, Turin, Italy.
Background: Exposure to asbestos in the workplace is currently recognized as one of the leading causes of work-related deaths, with more than half of deaths attributable to cancer.
Aims: The aim of this systematic literature review was to investigate the mental health and psychological distress of patients affected by asbestos-related diseases and their caregivers.
Methods: The review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.
Pulmonology
December 2025
Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium.
Sensors (Basel)
December 2024
Faculty of Mechanical Engineering, Lublin University of Technology, 36 Nadbystrzycka St., 20-618 Lublin, Poland.
This article presents a laboratory device by which the course of two signals can be detected using two types of sensors-strain gauges and the DEWESoft DS-NET measuring apparatus. The values of the coefficient of friction of the brake lining when moving against the rotating shell of the brake drum were determined from the physical quantities sensed by tensometric sensors and transformed into electrical quantities. The friction coefficient of the brake lining on the circumference of the rotating brake disc shell can be calculated from the known values measured by the sensors, the design dimensions of the brake, and the revolutions of the rotating parts system.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian National Workers' Compensation Authority (INAIL), Via Stefano Gradi 55, 00143 Rome, Italy.
Objectives: Occupational respiratory diseases represent a major public health concern worldwide. This study analyses the hospitalization costs and characteristics of four major occupational respiratory diseases: malignant mesothelioma (MM), sinonasal cancer (SNC), pneumoconiosis (PN), and hypersensitivity pneumonitis (HP). The findings are situated within the context of Italy's population trends and healthcare system, offering insights into the economic and clinical burden of these diseases.
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