Posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) are highly prevalent and comorbid among older adult male veterans. Both PTSD and OSA are independently associated with cognitive deficits in older adults, but little research regarding the impact of comorbid PTSD and OSA among older adults exists. The current study aimed to examine the independent and interactive effects of PTSD and OSA on cognitive functioning in older adult veterans. Older adult male veterans with ( = 106) and without PTSD ( = 69), ranging in age from 55 to 89 ( = 63.35). Participants underwent polysomnography evaluation to assess severity of OSA symptoms and comprehensive neuropsychological evaluation to assess cognitive functioning in 3 domains: attention and processing speed, learning and memory, and executive functioning. Multiple regression analyses showed that the interaction between PTSD and OSA did not predict cognitive performance. However, PTSD significantly predicted poorer attention and processing speed, and increased OSA severity predicted poorer learning and memory. While PTSD and OSA did not have a synergistic detrimental impact on cognition, each independently predicted poorer cognitive functioning within certain domains, suggesting that older adults with these comorbid conditions may experience a wider array of cognitive difficulties.

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http://dx.doi.org/10.1177/08919887221149132DOI Listing

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  • This study investigates the prevalence of obstructive sleep apnea (OSA) among veterans compared to nonveterans, using a national survey with over 15,000 veterans and nearly 5,000 nonveterans.
  • Results show a significantly higher prevalence of OSA in veterans (21%) compared to nonveterans (9%), with veterans diagnosed about 5 years earlier on average.
  • The findings underline the need for improved access to treatment for veterans, as well as further research on underdiagnosis in nonveterans, particularly among racial/ethnic minorities and those with PTSD.
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  • Obstructive sleep apnea (OSA) is prevalent among older adults, particularly those over 65, and its relationship with posttraumatic stress disorder (PTSD) requires further research for personalized treatment approaches.
  • The study utilized a cross-sectional design involving male Vietnam War veteran twins to examine the link between PTSD symptoms and OSA, employing in-laboratory polysomnography for evaluation.
  • Results indicated that a 15-point increase in PTSD symptom severity was correlated with a higher apnea-hypopnea index, suggesting that PTSD may significantly impact OSA severity.
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