Rapamycin in the context of Pascal's Wager: generative pre-trained transformer perspective.

Oncoscience

Insilico Medicine, Hong Kong Science and Technology Park, Hong Kong.

Published: December 2022

Large language models utilizing transformer neural networks and other deep learning architectures demonstrated unprecedented results in many tasks previously accessible only to human intelligence. In this article, we collaborate with ChatGPT, an AI model developed by OpenAI to speculate on the applications of Rapamycin, in the context of Pascal's Wager philosophical argument commonly utilized to justify the belief in god. In response to the query "Write an exhaustive research perspective on why taking Rapamycin may be more beneficial than not taking Rapamycin from the perspective of Pascal's wager" ChatGPT provided the pros and cons for the use of Rapamycin considering the preclinical evidence of potential life extension in animals. This article demonstrates the potential of ChatGPT to produce complex philosophical arguments and should not be used for any off-label use of Rapamycin.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796173PMC
http://dx.doi.org/10.18632/oncoscience.571DOI Listing

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