Context: There has been extensive focus on forensic odontology with an increase in the research for age estimation procedures. Teeth are biological markers for human age estimation. In adults, age estimation with a tooth has to be done by the analysis of cementum annulations, root transparency and determination of aspartic acid racemization. Various age estimation methods are known in literature; however, the reliability and relevance of these methods for the Indian population have seldom been studied.
Aim: To assess and compare age estimation by Drusini's method and Jeon's method and correlate chronological age and age estimation by both the methods in Indian Adults.
Objective: Comparative assessment of Drusini's method and Jeon's method for age estimation within Indian adults.
Subjects And Methods: Two hundred intraoral periapical radiovisuographs of the patients aged 20-69 years with optimum diagnostic quality radiographic images of permanent mandibular first molars were selected from the digital archive of the Department of Oral Medicine Diagnosis and Radiology from the dental college. Measurements were done using Drusini's and Jeon's methods and compared with the chronological age. A < 0.05 was considered statistically significant.
Statistical Analysis Used: Analysis of variance followed by Tukey's test, -test.
Results: Mean chronological age, estimated using Jeon's method and estimated by Drusini's method, was 30.77 ± 9.32, 29.790 ± 7.729 and 27.885 ± 8.190, respectively. This difference was statistically highly significant, whereas Jeon's method showed a strong positive correlation between chronological age and age.
Conclusions: The study concludes that Jeon's method is more accurate than Drusini's in the Indian population.
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http://dx.doi.org/10.4103/jomfp.jomfp_449_21 | DOI Listing |
Background: Age-related macular degeneration (AMD), a condition of multifactorial origin, is a major cause of irreversible vision loss in industrialized countries. The dry late stage of the disease, known as geographic atrophy (GA), is characterized by progressive loss of photoreceptor cells and retinal pigment epithelial cells in the central retina. An estimated 300 000 to 550 000 people in Germany suffer from GA.
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
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A.C. Camargo Cancer Center, São Paulo, Brazil.
Background: Oropharyngeal cancer (OPC) incidence is rising globally, predominantly in high-income countries due to human papillomavirus (HPV) infection. However, further data on OPC incidence in Brazil is needed. The aim of this study was to estimate the incidence, trends, and predictions of OPC in Brazilian population-based cancer registries (PBCRs) by period, sex, and topography.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Importance: During buprenorphine treatment for opioid use disorder (OUD), risk factors for opioid relapse or treatment dropout include comorbid substance use disorder, anxiety, or residual opioid craving. There is a need for a well-powered trial to evaluate virtually delivered groups, including both mindfulness and evidence-based approaches, to address these comorbidities during buprenorphine treatment.
Objective: To compare the effects of the Mindful Recovery Opioid Use Disorder Care Continuum (M-ROCC) vs active control among adults receiving buprenorphine for OUD.
JAMA Netw Open
January 2025
Department of Family Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Importance: There is limited evidence regarding the association between age at menopause and incident type 2 diabetes (T2D).
Objective: To investigate whether age at menopause and premature menopause are associated with T2D incidence in postmenopausal Korean women.
Design, Setting, And Participants: This population-based cohort study was conducted among a nationally representative sample from the Korean National Health Insurance Service database of 1 125 378 postmenopausal women without T2D who enrolled in 2009.
JAMA Pediatr
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Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Importance: Spontaneous reports have indicated that montelukast increases the risk of neuropsychiatric adverse events, and the US Food and Drug Administration added a boxed warning about these risks in 2020. However, the potential mechanism is not well understood, and the observational evidence is scarce, particularly in children.
Objective: To assess the potential association between the use of montelukast and the risk of neuropsychiatric adverse events in children and adolescents.
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