With the advancement in the study of keratoconjunctivitis sicca and the scope of its treatment, punctal plugs are being widely used for the therapeutic management of dry eye disease. With the emergence of 3D printing in medicine, 3D printing of punctal plugs that have an inbuilt drug delivery system and also that can be personalized from patient to patient according to their punctum size can be a great therapeutic option. Another benefit of the device is that its printing takes a short period of time and is cost-effective. This study aimed at making an open source design and 3D printing an efficient model of a punctal plug with an inbuilt drug delivery system that can be eventually used for the treatment of various ocular diseases that require frequent drug instillation or blockage of the nasolacrimal pathway. The 3D design for the punctal plug was made using the open source application, FreeCAD, and slicing was done using the application ChituBox. After that, the plugs were printed using the LCD printer Crealty LD-002R. The material used was resin that was compatible with the Crealty LD-002R. Punctal plugs with satisfactory results were printed using the LCD printer. The punctal plugs showed suitable structure and were also easily reproduced in the 3D printer without any complications or setbacks.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155558 | PMC |
http://dx.doi.org/10.4103/ijo.IJO_997_22 | DOI Listing |
Clin Ophthalmol
December 2024
Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Ocul Surf
December 2024
Department of Prof. Gabison, A. De Rothschild Foundation Hospital, Paris, France. Electronic address:
Purpose: Graft-versus-host disease (GVHD) is a common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). GVHD may affect several organs, including ocular manifestations, ranging from dry eye syndrome to sight-threatening corneal ulceration or perforation. Limited information is available about characteristics and treatments of ocular GVHD and its relation to general prognosis.
View Article and Find Full Text PDFMedicina (Kaunas)
October 2024
Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki City 852-8501, Japan.
: Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disorder characterized by the formation of intranuclear inclusions in cells. Adult-type NIID usually develops in elderly patients with various clinical manifestations and is sometimes accompanied by ocular symptoms. A case of adult-onset NIID with early and unique manifestations, including a progressive corneal defect and retinal changes, which are concerning at a young age, is reported.
View Article and Find Full Text PDFEye Contact Lens
November 2024
Department of Ophthalmology (J.J.M., N.E., W.C.F., A.M.F.), University of North Carolina, Chapel Hill, NC; Department of Ophthalmology (J.J.M.), University of Auckland, Auckland, New Zealand; Tricore Reference Laboratories (K.C.), Albuquerque, NM; Brooke Army Medical Center (E.A.), San Antonio, TX; Medical College of Wisconsin Department of Ophthalmology (N.E.), Milwaukee, WI; Campbell University School of Medicine (W.C.F.), Lillington, NC; Department of Pathology-Laboratory Medicine (P.G.), University of North Carolina School of Medicine, Chapel Hill, NC; and Department of Ophthalmology (A.M.F.), Duke University, Durham, NC.
Eye (Lond)
October 2024
Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
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