AI Article Synopsis
- Gastroschisis is an abdominal wall defect in infants often linked to growth issues.
- A study assessed the growth and body composition of infants with simple gastroschisis at birth, discharge, and 3 months, comparing them to healthy peers.
- Findings showed that these infants were lighter and smaller at both birth and 3 months, with lower fat-free mass, although their body fat percentage was similar to healthy infants and improved over time.
- Factors like male sex and nutrition methods influenced body composition differences.
Article Abstract
Background: Gastroschisis is an abdominal wall malformation usually associated with impaired growth.
Objective: To evaluate the growth and body composition of infants born with simple gastroschisis in a referral center.
Methods: This was a single-center, prospective case series of infants with simple gastroschisis who were measured at birth, at discharge, and at 3 months. Body composition was assessed via air-displacement plethysmography at discharge and at 3 months. The results were compared with those reported for healthy infants at an equivalent gestational age.
Results: Simple gastroschisis infants were lighter and smaller at birth and remained similar at 3 months. All anthropometric z scores decreased from birth to discharge, followed by an increase but not a full recovery toward 3 months. Overall, gastroschisis infants had a similar FM percentage, FM% (11.1 ± 4.7), but a lower FFM, FFM (2481 ± 478 g), at discharge. FM% (18.5 ± 5.3) decreased at 3 months, and FFM remained lower (3788 ± 722 g) but improved between the two exams. Boys had significantly more FFM than girls at both evaluations. The multiple regression analysis showed that male sex, prematurity, total parenteral nutrition duration, and exclusive breast milk diets were associated with differences in body composition.
Conclusions: Infants with simple gastroschisis cared for in a referral center experienced growth failure at discharge and showed a similar FM% but lower FFM than healthy infants. At 3 months, they exhibited smaller FM% and FFM, but FFM improved after the first exam, representing a better protein accretion.
Type Of Study: Prognostic.
Level Of Evidence: IV.
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| http://dx.doi.org/10.1016/j.jpedsurg.2022.11.005 | DOI Listing |
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Article Synopsis
- - This study focused on examining long-term gastrointestinal issues in children with gastroschisis, particularly comparing simple and complex cases, which involve more severe complications.
- - Researchers analyzed data from 315 children born with gastroschisis in Sweden from 1997 to 2016, finding that complex cases had a significantly higher risk of intestinal failure and bowel obstruction.
- - The findings indicated that complex gastroschisis cases faced much greater challenges, particularly in the first two years of life, with some children needing surgery to address these complications.
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