Background: Macromastia in adolescents is both physically and psychologically debilitating during a period in life when individuals are particularly vulnerable to peer pressure and social norms. Early recognition and intervention by both pediatricians and surgeons are critical to avoid unnecessary suffering. While reduction mammaplasty is the gold standard for the management of symptomatic macromastia in adults, the management of macromastia in pediatric patients remains controversial. In particular, there is great discussion regarding the timing of reconstructive breast surgery in pediatric patients.
Methods: A comprehensive review of the literature was performed to identify all articles related to macromastia in patients ≤16 years of age, the age at which full development is typically achieved in the United States. The etiologies of pediatric macromastia, approaches to management, and outcomes are summarized herein.
Findings: Pathological breast hypertrophy in pediatric patients is a rare finding and may occur secondary to juvenile hypertrophy of the breast (JHB) and pseudoangiomatous stromal hyperplasia (PASH). While medical management of these pathologies has been attempted with varying success, reduction mammaplasty is safe and effective in pediatric patients. There are, however, a number of pediatric-specific considerations that must be taken into account prior to surgery. We provide an algorithm for approaching pediatric macromastia.
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http://dx.doi.org/10.1016/j.bjps.2022.12.003 | DOI Listing |
Int J Surg Case Rep
January 2025
Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V Rabat, Morocco.
Introduction And Importance: Juvenile breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is a rare disorder characterized by rapid, excessive breast growth in prepubertal or peripubertal girls, with no apparent cause. Juvenile breast hypertrophy is considered one of the most challenging mastopathies to manage.
Case Presentation: We present the case of a 12-year-old Moroccan girl with virginal breast hypertrophy, who was successfully treated.
Plast Reconstr Surg Glob Open
September 2024
From the Division of Plastic Surgery, Ann and Robert H. Lurie Children's Hospital, Chicago, Ill.
Background: Although long-term benefits of reduction mammaplasty have been proven, the appropriate age for adolescent reduction mammaplasty has been highly debated due to possible need for revision surgery. Practitioners often delay offering breast reduction to adolescents below age 18 based on presumed insurance denial. We reviewed trends in insurance denial at a single children's hospital to analyze whether age and/or insurance carriers have a significant impact on coverage of breast reduction.
View Article and Find Full Text PDFAesthetic Plast Surg
December 2024
Division of Plastic and Reconstructive Surgery, Eastern Virginia Medical School, 301 Riverview Avenue, Norfolk, VA, USA.
Ann Plast Surg
April 2024
From the Division of Plastic Surgery, Department of Surgery, The Warren Alpert Medical School of Brown University, Providence, RI.
Introduction: Pediatric reduction mammoplasty has become increasingly common due to the obesity epidemic. While obesity remains the leading cause of macromastia leading to surgery, it may also be a risk factor for postoperative complications. This study examines the safety of pediatric reduction mammoplasty and the risk of obesity for complications following this procedure.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
June 2024
Department of Pathology, Tohoku University School of Medicine, Sendai, Miyagi 980-8575, Japan.
Context: Approximately 150 patients with juvenile gigantomastia have been reported in the literature but the underlying biologic mechanisms remain unknown.
Objective: To conduct extensive clinical, biochemical, immunochemical, and genetic studies in 3 patients with juvenile gigantomastia to determine causative biologic factors.
Methods: We examined clinical effects of estrogen by blockading estrogen synthesis or its action.
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