Background: Cognitive impairment among older people is an important public health problem in developing countries. Therefore, it is necessary to identify the subtypes of cognitive function among older people in China, and explore the transformation patterns and influencing factors.
Methods: Longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS) were used, and included 2140 women and 2049 men aged over 60 years. Latent profile and latent transition analysis (LPA<A) were used to identify subgroups and transitions between the profiles over time. Influencing factors were identified by multinomial logistic regression analysis.
Results: According to the LPA model, three subgroups of cognitive function were identified: Cognitive Impairment, Mild Cognitive Impairment (MCI) and Normal Cognitive Function. Concurrently, >50 % of participants were likely to progress to MCI after seven years, whereas participants with cognitive impairment had a probability of 54.2 % of transitioning to a better cognitive profile. Older adults are less likely to experience cognitive improvement, higher levels of education affect changes in cognition, and having depression are at a lower risk of cognitive decline.
Limitations: Due to the incompleteness of the cognitive assessment and the large time span, there was a certain bias in the classification and analysis of latent cognitive profiles.
Conclusion: This study identified three latent profiles among Chinese older people and showed the stability and heterogeneity. It demonstrated the effects of higher age or levels of education, and depression on changes in cognitive function in older people.
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http://dx.doi.org/10.1016/j.jad.2022.12.116 | DOI Listing |
Nutr Res
January 2025
Department of Molecular Medicine, University of Padova, Padova, Italy; IMDEA-Food, Madrid, Spain. Electronic address:
l-Theanine is a unique non-protein amino acid found abundantly in tea leaves. Interest in its potential use as a dietary supplement has surged recently, especially claims related to promoting relaxation and cognitive enhancement. This review surveys the chemistry, metabolism, and purported biological activities of l-theanine.
View Article and Find Full Text PDFJ Neurosurg
January 2025
Departments of1Biomedical Engineering.
Objective: Epilepsy is a common neurological disease affecting nearly 1% of the global population, and temporal lobe epilepsy (TLE) is the most common type. Patients experience recurrent seizures and chronic cognitive deficits that can impact their quality of life, ability to work, and independence. These cognitive deficits often extend beyond the temporal lobe and are not well understood.
View Article and Find Full Text PDFKidney360
January 2025
University of Manitoba, Winnipeg, MB, Canada.
Background: Cognition is a research priority for people living with chronic kidney disease (CKD), but identification of critical research questions is lacking. This study aimed to determine which cognition-related research questions are most important to CKD stakeholders.
Methods: A modified Delphi technique with 3 survey rounds was used.
PLoS One
January 2025
Substitutive Dental Sciences Department (Prosthodontics), College of Dentistry, Taibah University, Al Madinah, Saudi Arabia.
Background: This study aimed to investigate the quality and readability of online English health information about dental sensitivity and how patients evaluate and utilize these web-based information.
Methods: The credibility and readability of health information was obtained from three search engines. We conducted searches in "incognito" mode to reduce the possibility of biases.
PLoS One
January 2025
School of Nursing, Anhui Medical University, Hefei, Anhui, China.
Objective: To evaluate and compare the readability of information on different treatment options for breast cancer from WeChat public accounts, propose targeted improvement strategies based on the evaluation of the results of the various treatment options, and provide a reference for producers of WeChat public accounts from which to write highly readable information regarding breast cancer treatment options.
Methods: With "breast cancer" as keywords in April 2021, searches were implemented on Sogou WeChat website (https://weixin.sogou.
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