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Metabolic and physiological functions of Patatin-like phospholipase-A in plants.
Int J Biol Macromol
December 2024
National Institute of Plant genome Research, New Delhi 110067, India. Electronic address:
Article Synopsis
- Patatin-like phospholipase-A (pPLA) enzymes are found in both animals and plants, with plant pPLAs linked to the storage protein patatin from potatoes, but their functions in plants are not well understood compared to those in animals.* -
- Recent research has begun to unravel the roles of pPLAs in plants, focusing on their structural features and biochemical activities, particularly in lipid metabolism and accumulation of materials like lignin and cellulose.* -
- The review highlights the significance of pPLAs in important plant processes, including stress responses, interactions with pathogens, and overall plant development, which could aid in improving crop biotechnology.*
Ability of a dietary index based on the updated algorithm underpinning the Nutri-Score to discriminate food consumption and nutrient intake in a French population of children and adolescents.
Food Res Int
December 2024
Université Sorbonne Paris Nord and Université Paris Cité, INSERM, INRAE, CNAM, Center of Research in Epidemiology and StatisticS (CRESS), Nutritional Epidemiology Research Team (EREN), F-93017 Bobigny, France; Public Health Department, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris (AP-HP), Bobigny, France. Electronic address:
Introduction: Preventing chronic diseases among children and adolescents requires a comprehensive approach. The Nutri-Score, a front-of-pack nutrition labeling system, may play an important role in public health by enhancing overall nutritional quality of dietary intake, a key modifiable risk factor. The aim of this study was to investigate the ability of the 2015 and 2023 NS-NPM to discriminate food consumption and nutrient intake in a population of French children and adolescents.
View Article and Find Full Text PDFUpdate on Cannabidiol in Drug-Resistant Epilepsy.
Indian J Pediatr
January 2025
Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, SAS Nagar, Punjab, India.
Article Synopsis
- - CBD is emerging as a beneficial treatment for children with drug-resistant epilepsy (DRE), particularly for conditions like Dravet syndrome, Lennox Gastaut syndrome, and Tuberous sclerosis complex, with regulatory approval in multiple countries.
- - Clinical trials indicate that CBD can reduce seizure frequency and improve the quality of life for affected children, with a generally favorable safety profile, though minor side effects like sleepiness and diarrhea may occur.
- - Accessibility and cost remain significant issues, especially in lower-income regions such as India, prompting a discussion on the opportunities and hurdles of integrating CBD into clinical practice while navigating the evolving regulatory environment.
How to improve sustainability of nutrient dense diets for children and adolescents: an exemplary assessment in Germany.
Eur J Nutr
November 2024
Research Department of Child Nutrition, University Hospital of Pediatrics and Adolescent Medicine, St. Josef-Hospital, Ruhr-University, Bochum, Germany.
Article Synopsis
- The study focuses on improving the dietary guidelines for children and adolescents in Germany by applying the Planetary Health Diet Index (PHDI) to the Optimized Mixed Diet (OMD).
- The original OMD scored 68.24 points on the PHDI, highlighting strengths in fruits, vegetables, and fish while lacking in tubers, dairy, and red meat.
- After modifying the diet to include more nuts, legumes, and whole grains, the PHDI score improved to 81.51 points, indicating a significant increase in sustainability and nutrient density.
Update on Pediatric Surveillance Recommendations for PTEN Hamartoma Tumor Syndrome, DICER1-Related Tumor Predisposition, and Tuberous Sclerosis Complex.
Clin Cancer Res
November 2024
National Cancer Institute, Bethesda, MD, United States.
PTEN hamartoma tumor syndrome (PHTS), DICER1-related tumor predisposition (DICER1) and tuberous sclerosis complex (TSC) are rare conditions which each increase risk for distinct spectra of benign and malignant neoplasms throughout childhood and adulthood. Surveillance considerations for each of these conditions focus on patient and family education, early detection and multidisciplinary care. In this manuscript, we present updated surveillance recommendations and considerations for children and adolescents with PHTS, DICER1 and TSC and provide suggestions for further research in each of these conditions.
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