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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792965 | PMC |
http://dx.doi.org/10.3389/fmed.2022.1100846 | DOI Listing |
Int Braz J Urol
January 2025
Unidade de Pesquisa Urogenital - Universidade Estadual do Rio de Janeiro - Uerj, Rio de Janeiro, RJ, Brasil.
Pediatrics
December 2024
University of Colorado School of Medicine, Aurora, Colorado.
Value Health
November 2024
The Comparative Health Outcomes, Policy, and Economics (CHOICE) Institute, University of Washington, Seattle, WA, USA; The National Bureau of Economic Research, Cambridge, MA, USA. Electronic address:
Objectives: This study aims to understand the role of alternative pricing and financing mechanisms on the budget impact for payers and the risks and returns of manufacturers for gene therapies.
Methods: This article uses fundamental economic principles to interpret the implications of alternative pricing mechanisms in terms of the share of value appropriated by the manufacturer and how alternative financing mechanisms alter it. It demonstrates these concepts by studying the financial impacts for a payer and the manufacturer across alternative pricing and financing mechanisms that could be used by the US Centers for Medicare and Medicaid Services to pay for gene therapy for sickle cell disease.
Br J Haematol
December 2024
Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.
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