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Evaluation of Blood Biochemistry and Cardiopulmonary status of Hospitalized Covid-19 Patients in 3 Months Post Discharged Follow up Survey. | LitMetric

AI Article Synopsis

  • - The study followed 178 COVID-19 patients three months post-recovery, assessing cardiac and pulmonary health through various tests due to the systemic inflammation caused by the virus.
  • - Key findings revealed that many patients still showed pulmonary issues such as ground-glass opacities, while cardiac factors like PVCs decreased, and some lab results showed significant improvement.
  • - The conclusion emphasizes that even after recovery, patients experienced ongoing pulmonary changes and cardiac symptoms, highlighting the virus's lasting impact on multiple organ systems.

Article Abstract

Background: The new coronavirus causes systemic inflammation and damage to various organs. So, this study aimed to follow up patients with COVID -19 after recovery for three months by performing cardiac, pulmonary and laboratory tests.

Materials And Methods: This was a prospective cohort study of COVID-19 patients who were discharged from Baharloo Hospital. The diagnosis of COVID-19 was confirmed by PCR or long CT scan. Inclusion criteria were age over 18 years and patients with more than 50% of pulmonary involvement in lung CT scan. The patients were called to Baharloo hospital three months after recovery and were examined for cardiac, pulmonary and blood tests.

Result: Our study included 178 participants with mean age of 55.70, and 50.6% of them were male. Among pulmonary factors in the hospital, 71.9%, 15.7%,1.7%,19.1% and 53.4% had positive GGO, consolidation, reverse halo sign, traction bronchiectasis and vascular enlargement, respectively. After three months follow up, percentage of patients who had reticulation, honeycombing, fibrotic brand and bullae were 12%, 1.1%,8.4% and 0%, respectively. The Mean values of FVC and FEV1 were reported 4.21 and 3.01, respectively. Among Cardiac factors, positive PVC, PAC and mean Pap were decreased after three months. Only Growth in myalgia and Decreased sense of taste were statistically significant. Also, D dimer, UA protein, PMN, Ferritin CRP, PMN, LDH and HB amounts had decreased significantly.

Conclusion: Our study indicated that in addition to pulmonary changes, rapid damage to other organs and the occurrence of cardiac symptoms and changes in laboratory result were also reported in patients recovered from COVID-19.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791284PMC
http://dx.doi.org/10.1177/11795484221119332DOI Listing

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