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http://dx.doi.org/10.29399/npa.28375 | DOI Listing |
J Hist Neurosci
December 2024
Independent Researcher, Wilmington, North Carolina, USA.
Edward Reynolds Hun is easily eclipsed by his father, Thomas (1808-1896), and his younger brother, Henry (1854-1924), in historical accounts of the evolution of neurology as a clinical specialty and academic discipline in nineteenth-century America. His early educational pathway, including a postgraduate year in Paris, was typical for sons of the wealthy seeking a medical degree. On his return from Europe, he embarked on a research career in neuropsychiatry seeking to uncover biochemical and pathological underpinnings for psychiatric disorders.
View Article and Find Full Text PDFNeurocase
December 2024
Psiquiatria Geriátrica, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Lobotomy was a widespread neurosurgical procedure in the first half of the 20th century. It was used as a treatment for various mental disorders. The development of psychosurgeries in Brazil, their indications, effects, consequences, advancements, as well as the social context of the population subjected to it are revised herein.
View Article and Find Full Text PDFNeuroSci
September 2024
Nova Institute for Health, Baltimore, MD 21231, USA;
PET Clin
January 2025
Division for Technology and Innovation, The Intervention Center, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address:
This article explores the role of PET in the diagnosis and treatment of schizophrenia. PET imaging can reveal neurobiologic aspects such as cerebral blood flow, glucose metabolism, receptor function, and neuroinflammation in schizophrenia. It has supported the dopaminergic hypothesis and helped distinguish symptom types and severity.
View Article and Find Full Text PDFBrain Commun
October 2024
Department of Neuroinflammation, National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK.
Encephalitis lethargica, an epidemic neurological illness, typically involved a severe sleep disorder and progressive parkinsonism. A century later, our understanding relies on seminal descriptions, more recent historical research and the study of small numbers of possible sporadic cases. Theories around infection, environmental toxins, catatonia and autoimmune encephalitis have been proposed.
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