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Are we cultivating the perfect storm for a human avian influenza pandemic?
Biol Res
December 2024
Laboratory of Cellular and Molecular Inmunology, Fundacion Ciencia & Vida, Universidad San Sebastian, Avda. del Valle Norte 725, Huechuraba, 8580702, Santiago, Region Metropolitana, Chile.
The emergence of highly pathogenic avian influenza (HPAI) A H5N1 virus in dairy cattle marks a troubling new chapter in the ongoing battle against zoonotic diseases. Since its initial detection in 1955, the H5N1 virus has primarily been associated with poultry, posing significant threats to both animal and human health. However, recent outbreaks in U.
View Article and Find Full Text PDFA brewing storm: the impact of economic collapse on the access to antimicrobials in Lebanon.
J Glob Antimicrob Resist
June 2022
Postdoctoral Fellow, Cornell Atkinson Center for Sustainability; Department of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Sustainable food systems and nutrition in the 21st century: a report from the 22nd annual Harvard Nutrition Obesity Symposium.
Am J Clin Nutr
January 2022
Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Food systems are at the center of a brewing storm consisting of a rapidly changing climate, rising hunger and malnutrition, and significant social inequities. At the same time, there are vast opportunities to ensure that food systems produce healthy and safe food in equitable ways that promote environmental sustainability, especially if the world can come together at the UN Food Systems Summit in late 2021 and make strong and binding commitments toward food system transformation. The NIH-funded Nutrition Obesity Research Center at Harvard and the Harvard Medical School Division of Nutrition held their 22nd annual Harvard Nutrition Obesity Symposium entitled "Global Food Systems and Sustainable Nutrition in the 21st Century" in June 2021.
View Article and Find Full Text PDFAfucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.
Science
February 2021
Department of Experimental Immunohematology, Sanquin Research, Amsterdam, Netherlands.
Immunoglobulin G (IgG) antibodies are crucial for protection against invading pathogens. A highly conserved N-linked glycan within the IgG-Fc tail, which is essential for IgG function, shows variable composition in humans. Afucosylated IgG variants are already used in anticancer therapeutic antibodies for their increased activity through Fc receptors (FcγRIIIa).
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