AI Article Synopsis
- The rising abuse of drugs has raised significant public health and safety concerns, leading to the need for effective sensing platforms to detect these substances.
- Researchers developed a poly(ionic liquid) photonic crystal sphere that incorporates aggregation-induced emission (AIE) luminogens, enabling the detection of a wide variety of psychoactive drugs with varying affinities.
- This innovative sensing platform can be customized using ion-exchange, offering a flexible, efficient approach to create high-throughput sensing arrays without complex synthesis processes.
Article Abstract
Drugs of abuse has drawn intense attention due to increasing concerns to public health and safety. The construction of a sensing platform with the capability to identify them remains a big challenge because of the limitations of synthetic complexity, sensing scope and receptor extendibility. Here a kind of poly(ionic liquid) (PIL) photonic crystal spheres doped with aggregation-induced emission (AIE) luminogens was developed. As diverse noncovalent interactions involve in PIL moieties, the single sphere shows different binding affinity to a broad range of psychoactive substances. Furthermore, the dual-channel signals arising from photonic crystal structures and sensitive AIE-luminogens provide high-dimensional information for discriminative detection of targets, even for molecules with slight structural differences. More importantly, such single sphere sensing platform could be flexibly customized through ion-exchange, showing great extendibility to fabricate high-efficiency/high-throughput sensing arrays without tedious synthesis.
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| http://dx.doi.org/10.1002/chem.202203616 | DOI Listing |
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