AI Article Synopsis
- A solvent casting technique was employed to create biomimetic nanocomposite scaffolds using varying concentrations of Curcumin-loaded gold nanoparticles (Cur-AuNPs) combined with chitosan-sodium alginate.
- The physicochemical properties of the Cur-AuNPs and the resulting nanocomposites were analyzed through various characterization methods, focusing on their biocompatibility and antibacterial activity.
- These studies indicate that Cur-AuNPs integrated with biomimetic nanocomposites have potential applications for nanotheranostics in targeted therapies.
Article Abstract
A solvent casting technique was used for the preparation of biomimetic nanocomposites scaffolds at three various concentrations of Curcumin loaded gold nanoparticles (Cur-AuNPs-1, 1.5, and 2 ml) as filler materials with chitosan-sodium alginate composite. The physico-chemical properties of prepared Cu-Au NPs and biomimetic nanocomposites were analyzed using various characterization techniques. biocompatibility of biomimetic nanocomposites are determined using simulated body fluid for biomineralization property, HAp formation and phosphate buffer saline (PBS) for swelling property, protein adsorption. Antibacterial activity of Cur-Au NPs and their nanocomposites carried out against () and cytotoxicity of Cur-AuNPs is identified against UC-6 and MDA-MB 231 cell lines. The use of above studies and activity of Cur-AuNPs with contain biomimetic nanocomposites can adoptable for nanotheranostics.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09205063.2022.2151819 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!