An extract from the rhizomes of Cassumunar ginger ( Roscoe). was found to have significant -glucosidase inhibitory activity with an IC value of 6.3 g/mL. Two new phenylbutenoids, cassudimin A () and cassumunol N (), and seven known compounds (-) were isolated. Their structures and relative configurations of two new compounds were elucidated based on spectra interpretation. Compounds -, - showed more potent -glucosidase inhibitory activity than a positive control, acarbose (IC = 168.0 M). Dehydrozingerone () exhibited the most potent -glucosidase inhibition with an IC value of 8.3 M. Compounds and were found in rhizomes for the first time.
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