Unlabelled: The question of the course of lamellar macular holes (LMH) - favorable or progressive - remains controversial to this day. It is important to study the features of the course of this pathology in patients with epiretinal proliferation (EP).

Purpose: To establish the features of the course of lamellar macular holes with the presence of epiretinal proliferation.

Material And Methods: Clinical and instrumental monitoring was carried out in 48 patients with LMH divided into two groups: with the presence of EP (=27) and its absence (=21). The follow-up period lasted 15.9±2.3 months. The following parameters were assessed: changes in best corrected visual acuity (BCVA), mean retinal sensitivity (MRS) of the retina in 2- and 4-degree zones, subjective complaints; the main morphometric and morphostructural parameters of the retina were evaluated using optical coherence tomography (OCT).

Results: Patients with LMH and EP had lower initial BCVA, as well as, according to OCT, disruption of the ellipsoid zone and the presence of a foveal bump (37% and 22.2% of patients, respectively). During the follow-up, patients with EP showed an increase in subjective complaints, a statistically significant decrease in MRS in the 2-degree zone, and a decrease of the minimal retinal thickness.

Conclusion: LMH with EP are characterized by an unfavorable course, which is confirmed by a decrease in functional and anatomical parameters.

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Source
http://dx.doi.org/10.17116/oftalma202213806120DOI Listing

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