AI Article Synopsis
- - Africa's Lake Tanganyika basin has been identified as a hotspot for cholera outbreaks.
- - From 2001 to 2020, Vibrio cholerae O1 strains were collected from the Democratic Republic of the Congo and split into 2 out of the 5 clades of the AFR10 sublineage.
- - One of these clades became the most common due to a mutation in the parC gene, which reduced its susceptibility to the antibiotic ciprofloxacin.
Article Abstract
Africa's Lake Tanganyika basin is a cholera hotspot. During 2001-2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796204 | PMC |
| http://dx.doi.org/10.3201/eid2901.220641 | DOI Listing |
Publication Analysis
Top Keywords
vibrio cholerae
8
lake tanganyika
8
tanganyika basin
8
genomic microevolution
4
microevolution vibrio
4
cholerae lake
4
basin africa
4
africa africa's
4
africa's lake
4
basin cholera
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!