Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare, potentially fatal subtype of pityriasis lichenoides et varioliformis acuta (PLEVA). Herein, we present a rare case of a 14-year-old male without significant past medical history who was diagnosed with FUMHD without a clear inciting factor. He was effectively treated with systemic corticosteroids with complete resolution of symptoms.
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Febrile ulceronecrotic Mucha-Habermann disease - a case and treatment review.
Dermatol Online J
April 2024
Departamento de Medicina, Servico de Medicina Interna, Unidade Local de Saude de Matosinhos EPE, Portugal.
Article Synopsis
- * It often leads to serious complications including issues in the blood, lungs, heart, gut, and brain.
- * Treatment typically involves corticosteroids and immunosuppressants like methotrexate, with a case presented showing a gradual treatment strategy for a patient not responding well to methotrexate.
A case report of febrile ulceronecrotic Mucha-Habermann disease.
Transl Pediatr
April 2024
Department of Pediatric Critical Care Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Article Synopsis
- - FUMHD is a rare skin condition characterized by rapid onset of painful necrotic lesions, systemic symptoms like fever, and a complex diagnosis that requires ruling out other severe skin diseases.
- - A case study of a 13-year-old patient highlights a comprehensive treatment approach using corticosteroids, immunosuppressive therapy, and supportive care to manage the aggressive nature of FUMHD effectively.
- - The report emphasizes the importance of early diagnosis, prompt treatment, monitoring for infections, and addressing the psychological and social needs of the patient to enhance overall outcomes.
Febrile Ulceronecrotic Mucha-Habermann Disease Associated With Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature.
Am J Dermatopathol
April 2024
Department of Dermatology, Columbia University Irving Medical Center, New York, NY.
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- Mucha-Habermann disease (MHD) is an inflammatory skin condition with symptoms resembling cutaneous T-cell lymphoma, while its severe variant, febrile ulceronecrotic MHD (FUMHD), presents with systemic symptoms and ulcers.
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Rapid recovery in a child with febrile ulceronecrotic Mucha-Habermann disease following intravenous immunoglobulin administration.
Pediatr Dermatol
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Department of Pathology, Christian Medical College and Hospital, Vellore, India.
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- Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a serious skin disorder that can lead to severe health complications in children and requires prompt management to prevent fatal outcomes.
- Treatment options are limited due to the few reported cases and lack of substantial research, making it challenging to find effective therapies.
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Febrile Ulceronecrotic Mucha-Habermann Disease: A Case Report and Review of Literature in the Paediatric Population.
Acta Derm Venereol
April 2023
Department of Dermatology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) that is characterized by a large ulceronecrotic appearance with high fever and a variety of systemic symptoms. We report here a case of FUMHD in a 17-year-old male Chinese patient who was treated successfully with a combination therapy of methotrexate, methylprednisolone, and intravenous immunoglobulin. In addition, a literature review was conducted to summarize the key characteristics of paediatric FUMHD cases.
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