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Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study. | LitMetric

AI Article Synopsis

  • * A study analyzing surgical outcomes for metastatic spinal cord compression (MSCC) included 198 patients, primarily with prostate, hematological, and lung cancers.
  • * Results showed significant improvements in patients' motor function and pain relief post-surgery, highlighting the importance of personalized treatment plans and a collaborative medical approach for better quality of life.

Article Abstract

 The spinal column is one of the most prevalent regions for metastasis, with an increasing frequency of spinal metastases. Spinal cord metastatic tumor damages the vertebral body, weakens the spinal support, and exerts mass effect on the spinal cord. Overzealous surgical intervention does not provide any additional benefit in most of the spinal metastasis due to shorter life expectancy. The principal goal of this study is to analyze the outcome of various surgical treatments offered to patients with metastatic spinal cord compression (MSCC).  Retrospective cohort study including all patients that underwent surgical intervention for MSCC from March 2013 to March 2020.  A total of 198 patients were included, 113 males and 85 females; the mean age was 62 years. The most common primary cancer was prostate (21.71%) followed by hematological (20.07%) and lung (16.66%). At 6-month postsurgery, 68.68% of patients were Frankel grade D or E (vs. 23.23% preoperatively), 16.6% were grade C (vs 57% preoperatively), and 14.64% were grade A or B (vs. 19.69% preoperatively). Pain on numeric rating scale was decreased from 6.38 ± 3.08 to 3.39 ± 0.73 at 24 hours postsurgery and 1.94 ± 0.67 at 6 months.  This study found that the majority of patients, undergoing minimally invasive spinal stabilization and decompression for metastatic spinal tumors, have better quality of life, analgesia, and mobility. In conclusion, treatment for spinal metastases should be individualized and a multidisciplinary approach is needed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771617PMC
http://dx.doi.org/10.1055/s-0042-1758846DOI Listing

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