Simultaneous infections of tuberculosis and toxoplasmosis are uncommon in immunocompetent patients. We report a case of a 30-year-old male who presented with right eye redness and blurring of vision for one month. The visual acuities were hand movement and Snellen 20/30 in the right and left eyes, respectively. Panuveitis and scleritis were found in the right eye, together with dense vitritis and a large choroidal lesion that extended from the inferonasal to the superotemporal quadrants. B-scan ultrasonography of the right eye showed a choroidal detachment with scleral thickening and subtenon fluid. His IgM anti-Toxoplasma antibody was detected, and his QuantiFERON Gold testing was positive. Magnetic resonance imaging (MRI) of the orbit revealed an enhancing intraocular mass at the lateral and inferior aspects of the right globe. The diagnosis of right eye sclerouveitis with presumed tuberculosis and toxoplasmosis co-infections was made. He was treated with a course of oral azithromycin and anti-tubercular therapy along with systemic prednisolone and a topical steroid. The treatment reduced the inflammation; however, the patient suffered from a sequela of chronic uveitis with prolonged hypotony. Medical treatment alone may be insufficient in treating severe infective sclerouveitis, hence surgical intervention might be warranted to provide favorable clinical outcomes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769460PMC
http://dx.doi.org/10.7759/cureus.31726DOI Listing

Publication Analysis

Top Keywords

tuberculosis toxoplasmosis
12
infectious sclerouveitis
4
sclerouveitis immunocompetent
4
immunocompetent patient
4
patient probable
4
probable case
4
case simultaneous
4
simultaneous ocular
4
ocular tuberculosis
4
toxoplasmosis simultaneous
4

Similar Publications

Introduction: Tuberculosis (TB) remains the most common opportunistic infection and leading cause of death among individuals living with HIV/AIDS in Ethiopia. Its significant impact on morbidity and mortality underscores the crucial link between these two diseases. While the advent of antiretroviral therapy (ART) has led to a dramatic decline in mortality rates among HIV/AIDS patients, TB continues to pose a substantial threat.

View Article and Find Full Text PDF

This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2023 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and 10 non-MSs. Key statistics on zoonoses and zoonotic agents in humans, food, animals and feed are provided and interpreted historically. In 2023, the first and second most reported zoonoses in humans were campylobacteriosis and salmonellosis, respectively.

View Article and Find Full Text PDF
Article Synopsis
  • Ring-enhancing lesions are commonly found in patients with weakened immune systems, often due to conditions like HIV/AIDS or cancer, and can result from infections, tumors, or vascular issues.
  • A South American male in his 30s, with no previous medical history, arrived at the emergency department after a seizure, leading to brain imaging that revealed a solitary ring-enhancing lesion.
  • Despite thorough testing and consultations, including negative results for major infections, it was determined that the lesion stemmed from a prior infection, making this case significant given his lack of known risk factors.
View Article and Find Full Text PDF
Article Synopsis
  • HIV-related immunosuppression raises the risk of opportunistic infections (OIs) among patients, and a study in Honduras assessed the prevalence of these OIs in individuals who haven't received antiretroviral therapy (ART).
  • The study found that out of 110 treatment-naive HIV patients, 28.2% had OIs, with the most common being cryptococcosis, candidiasis, and tuberculosis.
  • The findings highlight a concerning rise in fungal OIs and indicate the need for better resource allocation for diagnosis and treatment in the Honduran healthcare system.
View Article and Find Full Text PDF

Objectives: The burden of SARS-CoV-2 infection in people living with HIV (PLHIV) in South Sudan is unknown.

Methods: We conducted a cross-sectional seroprevalence survey of SARS-CoV-2 immunoglobulin (Ig) G antibodies and other diseases of public health importance (strongyloidiasis, toxoplasmosis) in PLHIV in South Sudan during April 1, 2020-April 30, 2022. We used a multiplex SARS-CoV-2 immunoassay to detect IgG antibodies targeting the SARS-CoV-2 spike, receptor binding domain, and nucelocapsid (N) proteins, and antigens for other pathogens ().

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!