Background: Subthreshold depression is a risk factor for major depression. Psychotherapy is a kind of intervention for subthreshold depression. There have been many systematic reviews synthesized the evidence for its effectiveness toward subthreshold depression. However, there is currently no overview of these systematic reviews.
Objective: To undertake an overview of meta-analyses and systematic reviews to identify the efficacy of psychotherapy in subthreshold depression patients.
Methods: We will search several databases such as PubMed, Embase, the Cochrane Library, Web of Science, PsycINFO, CNKI, WanFang and VIP database, for systematic reviews and meta-analyses on psychotherapy in subthreshold depression patients. The search timeline will be from inception up to August 2022. Two researchers will screen related studies back-to-back. We will include studies that evaluate the efficacy of psychotherapy in subthreshold depression patients. We will evaluate the methodological quality, the reporting quality and the quality of evidence for outcomes by AMSTAR-2, the PRISMA 2020 checklist and the GRADE grading system. We will present the results of the overview in alignment with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The anticipated start and completion dates for this overview are 1 August 2022 and 30 December 2022, respectively.
Results: From this study, we will evaluate the methodological quality and the level of evidence of the included systematic reviews and meta-analyses, and evaluate the efficacy of psychotherapy in patients with subthreshold depression.
Implications: We will ascertain the efficacy of psychotherapy in subthreshold depression patients, to provide evidence to guide the treatment of subthreshold depression in the future.
Registration Number: Our research protocol has been registered with PROSPERO. The registration number of the protocol is CRD42021278871.
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http://dx.doi.org/10.3389/fpubh.2022.1017907 | DOI Listing |
Am J Geriatr Psychiatry
January 2025
Department of Psychiatry and Psychotherapy (JM, ME, NZ, KD, ES), Medical Center- University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:
Objective: This study investigates the association of loneliness during the COVID-19 pandemic and the course of depressive, anxiety and sleep symptoms after psychological treatment in older adults.
Methods: During the first wave of the pandemic in 2020, we assessed additional, original data of 132 participants aged ≥60 years who had completed psychological treatment for late-life depression (LLD) in the context of a multicenter, randomized controlled trial (CBT-late). We measured loneliness using the UCLA Loneliness Scale.
J Gerontol B Psychol Sci Soc Sci
January 2025
Department of Radiology, Huaxi MR Research Center (HMRRC), Institution of Radiology and Medical Imaging, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Objectives: Subthreshold depression (SD) is common in the older population, more so in females than males, and can lead to serious physical and mental ill-health. However, the underlying neurobiology remains unclear. This study used multimodal magnetic resonance imaging (MRI) to investigate the topological organization and coupling of the structural and functional brain networks in older women with SD.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department Neurology, Upper Silesian Medical Center named After Prof. Leszek Giec, ul. Ziołowa 45/47, 40-635 Katowice, Poland.
Lower back pain (LBP) is a common condition affecting primarily populations in developed countries, placing a significant burden on public health systems around the world. A high rate of pain recurrence increases the risk of developing a chronic syndrome and the occurrence of complex psychosocial and professional problems. Symptoms lasting longer than 12 weeks are associated with the risk of sleep problems, depression, and anxiety.
View Article and Find Full Text PDFProstaglandins Leukot Essent Fatty Acids
January 2025
School of Life and Health Sciences, University of Roehampton, London, UK. Electronic address:
Background: The long-chain omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have beneficial effects in depression, and these effects may be mediated via changes in functional brain connectivity. However, little is known about these effects in those with subthreshold depression.
Methods: 15 Participants aged 18-29 years with Patient Health Questionnaire-8 (PHQ-8) scores ≥ 4 and Generalised Anxiety Disorder Assessment-7 (GAD-7) scores ≥ 5, underwent resting-state functional magnetic resonance imaging.
Am J Transl Res
December 2024
Psychological Medicine Center, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830000, Xinjiang Uygur Autonomous Region, China.
Objective: To explore the current status of subthreshold depression in young and middle-aged breast cancer patients and its influencing factors, in order to guide early identification and intervention in clinical settings.
Methods: The study included 385 young and middle-aged cancer patients treated at the First Affiliated Hospital of Xinjiang Medical University from June 2023 to June 2024. Standardized scales were used to evaluate sub-threshold depression, psychological resilience, and self-perceived burden.
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