, an emerging fungus causing peritonitis in a patient receiving peritoneal dialysis.

Med Mycol Case Rep

Center of Excellence in Kidney Metabolic Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.

Published: March 2023

Fungal peritonitis (FP) is usually associated with poor patient outcomes and is mostly caused by non- species. We present a -associated peritonitis in a 68-year-old woman with end-stage kidney disease on peritoneal dialysis (PD). Biochemical profiling of the cultured yeast of the effluent sample did not adequately identify the yeast. Hence, molecular phylogeny and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) mass spectroscopy were employed which correctly identified the causative species, . PD catheter was removed and oral fluconazole was promptly started according to the 2022 International Society for PD (ISPD) Peritonitis Guidelines. However, the patient achieved only a partial clinical response and eventually died. The susceptibility test showed that the pathogen was susceptible to amphotericin B and voriconazole but resistant to other triazoles. This report underlines the importance of identifying the species, though rarely reported, and the drug susceptibility of the organism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772606PMC
http://dx.doi.org/10.1016/j.mmcr.2022.11.002DOI Listing

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