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| http://dx.doi.org/10.3389/fpsyg.2022.1020454 | DOI Listing |
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Objectives: To understand the competitive position of the UK in comparison to Europe and the USA for haematological cancer clinical research.
Design: Using commercially available databases, clinical trial numbers, their effectiveness and publication outputs were evaluated in two analyses: a macrodevelopment and a research activity and performance analysis.
Data Sources: The following databases were used for this analysis: Organisation for Economic Co-operation and Development, Thomson Reuters Incidence and Prevalence, the Cortellis Clinical Trial Intelligence, the Clarivate Cortellis Innography Patent Intelligence, Thomson-Reuters Cortellis Regulatory Intelligence, Thomson Reuters Web of Science and data from the Centre for Medicine Research (CMR).
Personal resilience, good leadership, and a psychologically safe culture play a mitigating role on the impact of patient safety events.
J Am Vet Med Assoc
December 2024
4School of Social Work, Columbia University, New York, NY.
Objective: To assess the impact of patient safety events on veterinary professionals and identify factors influencing their responses.
Methods: This was an experimental study, wherein a total of 2,182 veterinary professionals in the US, including veterinarians, technicians, assistants, client service providers, and managers/directors, were given an anonymous online survey utilizing the Second Victim Experience and Support Tool, Brief Resilience Scale, and Team Psychological Safety Scale.
Results: The majority of participants reported having experienced at least 1 patient safety event within the last 12 months.
ELECTROPHYSIOLOGICAL CHANGES IN THE PARTICIPANTS OF THE LIQUIDATION OF THE CONSEQUENCES OF THE CHORNOBYL ACCIDENT AND THE MILITARY PERSONNEL OF THE UKRAINIAN DEFENSE FORCES RECOVERING FROM CORONAVIRUS DISEASE (COVID-19).
Probl Radiac Med Radiobiol
December 2024
State Institution «National Research Center of Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Objective: to conduct a clinical and neurophysiological study of Chornobyl clean-up workers and military personnelof the Armed Forces of Ukraine (AFU) with previous coronavirus disease (COVID-19) and individuals of the comparison groups to study the impact of long-term effects of ionizing radiation, psychoemotional stress and previouscoronavirus infection on cerebral functioning.
Materials And Methods: A prospective clinical study of Chornobyl clean-up workers and servicemen of the ArmedForces of Ukraine (AFU) who had coronavirus disease (COVID-19) and individuals of the comparison groups. Themain group - 30 males participated in liquidating the consequences of the Chornobyl Nuclear Power Plant (ChNPP)accident with previously verified COVID-19 (Chornobyl clean-up workers).
Social factors affecting home-based end-of-life care for patients with cancer and primary caregivers.
Support Care Cancer
December 2024
Division of Legal Medicine, Shiga University of Medical Science, Otsu, Japan.
Objective: This study aimed to explore the social factors of patients and caregivers, including those related to their wishes for home-based end-of-life care that influence its fulfillment.
Methods: A secondary analysis was conducted using the dataset (home-based end-of-life care N = 625, hospital end-of-life care N = 7603) Comprehensive patient-based survey conducted by The Study on Quality Evaluation of Hospice and Palliative Care by Bereaved Caregivers (J-HOPE 4) and multivariate analysis (multiple logistic regression) to explore the impact of social factors of patients and caregivers on the fulfillment of home-based end-of-life care. The explanatory variables included 11 social factors of patients, such as age and sex, and 18 social factors of primary caregivers.
Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry.
Rheumatol Ther
December 2024
Division of Paediatric Rheumatology and Autoinflammation Reference Centre Tübingen, Department of Paediatrics, University Hospital Tübingen; Member of ERN-RITA, Tübingen, Germany.
Introduction: Interim analysis of the long-term safety and effectiveness of canakinumab, at a patient level, in the mevalonate kinase deficiency/hyperimmunoglobulin-D syndrome (MKD/HIDS) cohort of the RELIANCE registry.
Methods: From June 2018, the RELIANCE registry enrolled paediatric (aged ≥ 2 years) and adult patients (aged ≥ 18 years) with MKD/HIDS who were receiving canakinumab as part of their routine medical care. Safety, physician- and patient-reported measures of disease activity and dosing patterns were evaluated at baseline and every 6 months until end-of-study visit.
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