AI Article Synopsis
- The exact causes of asthma are not fully understood, but respiratory infections, particularly those caused by rhinovirus (RV), may trigger or worsen the condition.
- Understanding the connection between viral infections and asthma can help address differences in immune responses between viral infections and allergies.
- The complexity of RV-induced asthma involves both the immune response to the virus and allergic reactions triggered by various cytokines, highlighting the need to explore both RV infections and host defense mechanisms for a clearer understanding.
Article Abstract
While the aetiology of asthma is unclear, the onset and/or exacerbation of asthma may be associated with respiratory infections. Virus-induced asthma is also known as virus-associated/triggered asthma, and the reported main causative agent is rhinovirus (RV). Understanding the relationship between viral infections and asthma may overcome the gaps in deferential immunity between viral infections and allergies. Moreover, understanding the complicated cytokine networks involved in RV infection may be necessary. Therefore, the complexity of RV-induced asthma is not only owing to the response of airway and immune cells against viral infection, but also to allergic immune responses caused by the wide variety of cytokines produced by these cells. To better understand RV-induced asthma, it is necessary to elucidate the nature RV infections and the corresponding host defence mechanisms. In this review, we attempt to organise the complexity of RV-induced asthma to make it easily understandable for readers.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781665 | PMC |
| http://dx.doi.org/10.3390/v14122616 | DOI Listing |
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