The research on the electroencephalography (EEG)-based brain-computer interface (BCI) is widely utilized for wheelchair control. The ability of the user is one factor of BCI efficiency. Therefore, we focused on BCI tasks and protocols to yield high efficiency from the robust EEG features of individual users. This study proposes a task-based brain activity to gain the power of the alpha band, which included eyes closed for alpha response at the occipital area, attention to an upward arrow for alpha response at the frontal area, and an imagined left/right motor for alpha event-related desynchronization at the left/right motor cortex. An EPOC X neuroheadset was used to acquire the EEG signals. We also proposed user proficiency in motor imagery sessions with limb movement paradigms by recommending motor imagination tasks. Using the proposed system, we verified the feature extraction algorithms and command translation. Twelve volunteers participated in the experiment, and the conventional paradigm of motor imagery was used to compare the efficiencies. With utilized user proficiency in motor imagery, an average accuracy of 83.7% across the left and right commands was achieved. The recommended MI paradigm via user proficiency achieved an approximately 4% higher accuracy than the conventional MI paradigm. Moreover, the real-time control results of a simulated wheelchair revealed a high efficiency based on the time condition. The time results for the same task as the joystick-based control were still approximately three times longer. We suggest that user proficiency be used to recommend an individual MI paradigm for beginners. Furthermore, the proposed BCI system can be used for electric wheelchair control by people with severe disabilities.
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http://dx.doi.org/10.3390/s22249788 | DOI Listing |
J Med Internet Res
March 2025
Division of Emergency Medicine, Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Background: Stroke treatment has significantly improved over the last decades, but the complexity of stroke cases requires specialized care through dedicated teams with specific knowledge and training. The National Institutes of Health Stroke Scale (NIHSS), widely used to assess neurological deficits and make treatment decisions, is reliable but requires specific training and certification. The traditional didactic training method, based on a video, may not adequately address certain NIHSS intricacies nor engage health care professionals (HCPs) in continuous learning, leading to suboptimal proficiency.
View Article and Find Full Text PDFJ Infect
March 2025
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangwangmiao Street 12, Xuanwu District, Nanjing 210042, Jiangsu Province, China; Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, Jiangsu Province, China. Electronic address:
Objectives: The rapid plasma reagin (RPR) test, a traditional method for diagnosing syphilis and evaluating treatment efficacy, relies on subjective interpretation and requires high technical proficiency. This study aimed to develop and validate a user-friendly RPR-artificial intelligence (AI) interpretative tool.
Methods: A dataset comprising 600 images of photographed RPR cards from 276 negative and 223 positive RPR samples was used for model development.
Nat Protoc
March 2025
Data Mining and Modelling for Biomedicine, VIB Center for Inflammation Research, Ghent, Belgium.
Ligand-receptor interactions constitute a fundamental mechanism of cell-cell communication and signaling. NicheNet is a well-established computational tool that infers ligand-receptor interactions that potentially regulate gene expression changes in receiver cell populations. Whereas the original publication delves into the algorithm and validation, this paper describes a best practices workflow cultivated over four years of experience and user feedback.
View Article and Find Full Text PDFSci Adv
February 2025
Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.
Recent advancements in virtual reality (VR) and augmented reality (AR) have strengthened the bridge between virtual and real worlds via human-machine interfaces. Despite extensive research into biophysical signals, gustation, a fundamental component of the five senses, has experienced limited progress. This work reports a bio-integrated gustatory interface, "e-Taste," to address the underrepresented chemical dimension in current VR/AR technologies.
View Article and Find Full Text PDFPrecis Chem
February 2025
Department of Chemistry, York University, Toronto, Ontario, Canada M3J 1P3.
Equilibrium constants are essential for understanding and predicting the behavior of chemical systems across various scientific disciplines. Traditionally, these constants are computed via nonlinear regression of reaction isotherms, which show the dependence of the unreacted fraction of one reactant on the total concentration of another reactant. However, while these equilibrium constants can be precise (with small random errors), they may also be grossly inaccurate (with large systematic errors), leading to potential misinterpretations.
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