It is important to create new generations of materials that can destroy multidrug-resistant bacterial strains, which are a serious public health concern. This study focused on the biosynthesis of an essential oil entrapped in titanium dioxide (TiO) calcium alginate-based microspheres. In this research, calcium alginate-based microspheres with entrapped TiO nanoparticles and cinnamon essential oil (CI-TiO-MSs) were synthesized, using an aqueous extract of seeds for TiO nanoparticle preparation, and the ionotropic gelation method for microsphere preparation. The microspheres obtained were spherical, uniformly sized, microporous, and rough surfaced, and they were fully loaded with cinnamon essential oil and TiO nanoparticles. The synthesized microspheres were analyzed for antibacterial activity against the clinical multidrug-resistant strain of . Disc diffusion and flow cytometry analysis revealed strong antibacterial activity by CI-TiO-MSs. The synthesized CI-TiO-MSs were characterized by the SEM/EDX, X-ray diffraction, and FTIR techniques. Results showed that the TiO nanoparticles were spherical and 99 to 150 nm in size, whereas the CI-TiO-MSs were spherical and rough surfaced. Apoptosis analysis and SEM micrography revealed that the CI-TiO-MSs had strong bactericidal activity against . The in vitro antibacterial experiments proved that the encapsulated CI-TiO-MSs had strong potential for use as a prolonged controlled release system against multidrug-resistant clinical .
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http://dx.doi.org/10.3390/pharmaceutics14122764 | DOI Listing |
ACS Appl Mater Interfaces
December 2024
Key Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, P.R. China.
Phosphopeptide enrichment methods based on commercial TiO suffer from difficulties in regulating intermolecular interactions, resulting in low coverage rate and the loss of information on multiphosphorylation sites, thereby limiting comprehensive phosphoproteomic analysis. In this work, MXene TiCT was incorporated into the design of enrichment materials, with its surface structure functionalized and regulated to address the low elution efficiency of TiO for multiphosphorylated peptides. Upon oxidation treatment, the TiCT material formed numerous uniformly distributed TiO nanoparticles on the surface of TiCT-O, providing abundant affinity sites (Ti-O) for selective phosphopeptide enrichment.
View Article and Find Full Text PDFEnviron Sci Technol
December 2024
State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Chemical control of head blight (FHB) in wheat plants is often challenged by the resistance outbreak and deoxynivalenol (DON) accumulation. Developing green partners for fungicides is crucial for reducing fungal growth, mycotoxin contamination, and agricultural fungicides input. Herein, we investigated the mechanism of MgO nanoparticles (NPs) in controlling FHB.
View Article and Find Full Text PDFACS Omega
December 2024
Department of Biomedical Engineering, Universidad de los Andes, Bogotá 111711, Colombia.
Exposure to high temperatures during indoor and outdoor activities increases the risk of heat-related illness such as cramps, rashes, and heatstroke (HS). Fatal cases of HS are ten times more common than serious cardiac episodes in sporting scenarios, with untreated cases leading to mortality rates as high as 80%. Enhancing thermal comfort can be achieved through heat loss in enclosed spaces and the human body, utilizing heat transfer mechanisms such as radiation, conduction, convection, and evaporation, which do not require initial energy input.
View Article and Find Full Text PDFLuminescence
December 2024
Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, Saudi Arabia.
This study investigates the optical, mechanical, and antimicrobial properties of polypropylene (PP) fibers enhanced with titanium dioxide (TiO) and zinc oxide (ZnO) nanoparticles. Using a Mach-Zehnder interferometric system, we examined the refractive indices, birefringence, and opto-mechanical behavior of blank PP, PP/TiO, and PP/ZnO nanocomposite fibers under various conditions, including different polarization orientations and during cold drawing processes. The 2D Fourier transform algorithm is employed to analyze interferometric data, enabling precise measurements of refractive index profiles and birefringence.
View Article and Find Full Text PDFMicrob Cell Fact
December 2024
Botany and Microbiology Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
This comprehensive review explores the emergence of titanium dioxide nanoparticles (TiO-NPs) as versatile nanomaterials, particularly exploring their biogenic synthesis methods through different biological entities such as plants, bacteria, fungi, viruses, and algae. These biological entities provide eco-friendly, cost-effective, biocompatible, and rapid methods for TiO-NP synthesis to overcome the disadvantages of traditional approaches. TiO-NPs have distinctive properties, including high surface area, stability, UV protection, and photocatalytic activity, which enable diverse applications.
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