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Serotyping and Antimicrobial Susceptibility Profiling of Isolated from Diseased Swine in Brazil. | LitMetric

Serotyping and Antimicrobial Susceptibility Profiling of Isolated from Diseased Swine in Brazil.

Pathogens

Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of São Paulo, Av Prof Dr Orlando Marques de Paiva, 87, São Paulo 05508-270, SP, Brazil.

Published: November 2022

is one of the major pathogens in swine intensive production systems. To date, 15 serovars have been described, and the prevalence of these serotypes in different geographical regions has been identified by several methods. outbreaks could be controlled with vaccination if it were not for serovar diversity and limited cross-serovar protection; consequently, antibiotic therapy continues to be necessary for infection control. Here, we present the isolation, identification, serotyping, and antibiotic susceptibility profiling of from diseased swine in Brazil. A total of 105 strains, originating from nine different Brazilian states, were evaluated, and serotypes 4 and 5 were found to be the most prevalent (27.6% and 24.8% respectively). Aminoglycosides, florfenicol, tiamulin, and β-lactams were tested, and they presented lower resistant rates against strains. The highest resistance rates were observed against tylosin (97.1%), sulfadimethoxine (89.5%), danofloxacin (80%), trimethoprim/sulfamethoxazole (62.5%), enrofloxacin (54.3%), and clindamycin (50.5%). Multidrug resistance was detected in 89.5% of tested strains, and a total of sixty resistance profiles were identified. The cluster analysis of resistance patterns showed no correlation with the isolation year or serotype.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785225PMC
http://dx.doi.org/10.3390/pathogens11121443DOI Listing

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