This study explores the effect of geometric limitations on the achievable Purcell factor for single emitters in dielectric structures by employing topology optimization as an inverse design tool to maximize the local density of states. Nanobeams of different lengths with varying fixed central bridge widths are considered to investigate the impact of footprint and geometric length-scale. In single-mode photonic cavities, the Purcell factor is known to be proportional to the ratio of the quality factor Q to the effective mode volume V. Analysis of the optimized nanocavities shows a trade-off between quality factor and mode volume as a function of geometric limitations. Crucially, the design exhibiting the largest Purcell enhancement does not have the highest Q nor the lowest V found in the design pool. On the contrary, it is found that Q consistently drops along with decreasing V as the minimum allowed geometric length-scale decreases while the Purcell factor increases. Finally, the study provides insight into the importance of Q and V for enhancing the Purcell factor under geometric limitations.
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http://dx.doi.org/10.1364/OE.474686 | DOI Listing |
Nanophotonics
January 2025
Departamento de Ingeniería Electrónica, E.T.S.I. de Telecomunicación, Instituto de Sistemas Optoelectrónicos y Microtecnología (ISOM), Universidad Politécnica de Madrid, Madrid, 28040 Spain.
Polar biaxial crystals with extreme anisotropy hold promise for the spatial control and the manipulation of polaritons, as they can undergo topological transitions. However, taking advantage of these unique properties for nanophotonic devices requires to find mechanisms to modulate dynamically the material response. Here, we present a study on the propagation of surface phonon polaritons (SPhPs) in a photonic architecture based on a thin layer of α-MoO deposited on a semiconducting 4H-SiC substrate, whose carrier density can be tuned through photoinduction.
View Article and Find Full Text PDFACS Nano
January 2025
Institute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Controlling the light emitted by individual molecules is instrumental to a number of advanced nanotechnologies ranging from super-resolution bioimaging and molecular sensing to quantum nanophotonics. Molecular emission can be tailored by modifying the local photonic environment, for example, by precisely placing a single molecule inside a plasmonic nanocavity with the help of DNA origami. Here, using this scalable approach, we show that commercial fluorophores may experience giant Purcell factors and Lamb shifts, reaching values on par with those recently reported in scanning tip experiments.
View Article and Find Full Text PDFLight Sci Appl
January 2025
State Key Laboratory of Optical Fiber and Cable Manufacture Technology, Institute of Nanoscience and Applications, Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China.
Colloidal quantum dots (CQDs) are attractive gain media due to their wavelength-tunability and low optical gain threshold. Consequently, CQD lasers, especially the surface-emitting ones, are promising candidates for display, sensing and communication. However, it remains challenging to achieve a low-threshold surface-emitting CQD laser array with high stability and integration density.
View Article and Find Full Text PDFFront Oncol
December 2024
Research & Development, SMURF-Therapeutics, Inc., Providence, RI, United States.
The SMAD-specific E3 ubiquitin protein ligase 2 (SMURF2) has emerged as a critical regulator in cancer biology, modulating the stability of Hypoxia-Inducible Factor 1-alpha (HIF1α) and influencing a network of hypoxia-driven pathways within the tumor microenvironment (TME). SMURF2 targets HIF1α for ubiquitination and subsequent proteasomal degradation, disrupting hypoxic responses that promote cancer cell survival, metabolic reprogramming, angiogenesis, and resistance to therapy. Beyond its role in HIF1α regulation, SMURF2 exerts extensive control over cellular processes central to tumor progression, including chromatin remodeling, DNA damage repair, ferroptosis, and cellular stress responses.
View Article and Find Full Text PDFFront Plant Sci
November 2024
Plant Genetic Research Unit, United States Department of Agriculture - Agricultural Research Service (USDA-ARS), University of Missouri, Columbia, MO, United States.
Soybean is a major legume crop cultivated globally due to the high quality and quantity of its seed protein and oil. However, drought stress is the most significant factor that decreases soybean yield, and more than 90% of US soybean acreage is dependent on rainfall. Water use efficiency (WUE) is positively correlated with the carbon isotopic ratio C/C (C13 ratio) and selecting soybean varieties for high C13 ratio may enhance WUE and help improve tolerance to drought.
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