Maquiroside A, a new cardiac glycoside, was isolated from the Peruvian plant Maquira calophylla. The structure was established using spectroscopic methods, and the aglycone was found to be cannogenol. The sugar portion was identified as D-cymarose. Maquiroside A demonstrated activity against the KB cell culture.
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http://dx.doi.org/10.1021/np50050a015 | DOI Listing |
iScience
December 2024
Research Centre for Plant Metabolomics, Department of Biochemistry, University of Johannesburg, Johannesburg, South Africa.
We present the results of a GC-MS and UHPLC-MS analysis of residue recovered from the marrow cavity of a 7,000-year-old bovid femur from Kruger Cave, South Africa. The femur was filled with an unknown substance into which were embedded three bone arrowheads, indicating that the femur served as a quiver. Our results reveal the presence of digitoxin and strophanthidin, both cardiac glycosides associated with hunting poisons.
View Article and Find Full Text PDFChem Biodivers
December 2024
Fudan University, School of Pharmacy, Jinke Road 3728, Shanghai, CHINA.
Two undescribed cardiac glycosides, strasperoside K (1) and L (2), together with five known analogues (3-7), were isolated from Streblus asper Lour. Their structures were elucidated on the basis of spectroscopic analysis and chemical methods. The inhibitory activities of isolated compounds against porcine epidemic diarrhea virus (PEDV) and six strains of pathogenic bacteria were evaluated.
View Article and Find Full Text PDFMicrosc Res Tech
December 2024
Phytomedicine, Molecular Toxicology, and Computational Biochemistry Research Laboratory (PMTCB-RL), Department of Biochemistry, Bowen University, Iwo, Nigeria.
Croton lobatus L. and Croton zambesicus Mull. Arg.
View Article and Find Full Text PDFJ Mycol Med
December 2024
Laboratory of Engineering, Electrochemistry, Modeling and Environment Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Datura Stramonium is a well-known and important medicinal plant that is widely used in various medical systems to treat conditions such as asthma, diabetes, and inflammatory diseases. The aim of this study was to prepare extracts of D. stramonium seeds in different solvent polarities for assessing phytochemical potential, in vitro biological activities, and molecular docking studies.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
October 2024
National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Xueshuan Xinmaining Tablets and Capsules are two Chinese patent medicines with the same prescription, different preparation methods but the same function of replenishing Qi, activating blood, opening orifices, and relieving pain. Xueshuan Xinmaining Capsules were qualitatively analyzed by UPLC-Q/TOF-MS for the first time, and 61 compounds were identified, including 9 phenolic acids, 10 bufadienolides, 15 saponins, 5 bile acids, and 22 other compounds. The chemical composition was slightly different between Xueshuan Xinmaining Tablets and Capsules.
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