Micro multi-grooves are important functional structures widely used in new heat exchanger types, chemical reactors, and other applications. Electrolytic broaching is an efficient and low-cost technology for processing micro multi-grooves. In the conventional electrolytic broaching of multi-grooves, the cathode tools are usually designed as a wedge-shaped tooth structure array with a constant tooth width, and the sidewalls are covered with insulating layers. The machined groove sidewall is always tapered because of stray current corrosion, which strongly affects the groove contour accuracy. Cathode tools with variable tooth width structures are proposed to solve this problem. Based on the simulation results of the electrolytic broaching anode forming process, the optimal front tooth width is obtained through the golden section optimization method, and comparative tests of the conventional and optimized cathode tools were carried out. At an electrochemical broaching feed rate of 120 mm/min, array microgrooves with widths of about 550 μm and depths of about 520 μm were processed. With the optimized variable tooth width tool, the sidewall tapers of the grooves were reduced from 7.254° to 0.268°. The experimental results verify the effectiveness of the simulation and cathode structure optimization.
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http://dx.doi.org/10.3390/mi13122062 | DOI Listing |
Micromachines (Basel)
November 2022
College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics & Astronautics, 29 Yu Dao Jie Street, Nanjing 210016, China.
Micro multi-grooves are important functional structures widely used in new heat exchanger types, chemical reactors, and other applications. Electrolytic broaching is an efficient and low-cost technology for processing micro multi-grooves. In the conventional electrolytic broaching of multi-grooves, the cathode tools are usually designed as a wedge-shaped tooth structure array with a constant tooth width, and the sidewalls are covered with insulating layers.
View Article and Find Full Text PDFWater Environ Res
April 2021
Department of Civil and Environmental Engineering, University of Alberta, Edmonton, Alberta, Canada.
Alberta is a major center for oil and gas production, and correspondingly harbors hundreds of unresolved contamination sites by environmental hazards such as benzene (C H ). Due to its cost-effectiveness, bioremediation has become a promising strategy for C H removal. Contamination sites typically take on an anaerobic context, which complicates the energetics of contamination sites and is a subject that is scarcely broached in studies of Albertan sediments.
View Article and Find Full Text PDFDrug Dev Ind Pharm
October 2016
c Pfizer Inc. , Sandwich , Kent , UK.
A model is presented for determining the time when an active pharmaceutical ingredient in tablets/powders will remain within its specification limits during an in-use period; that is, when a heat-induction sealed bottle is opened for fixed time periods and where tablets are removed at fixed time points. This model combines the Accelerated Stability Assessment Program to determine the impact on degradation rates of relative humidity (RH) with calculations of the RH as a function of time for the dosage forms under in-use conditions. These calculations, in a conservative approach, assume that the air inside bottles with broached heat-induction seals completely exchanges with the external environment during periods when the bottle remains open.
View Article and Find Full Text PDFJ Endod
April 2014
Loma Linda University, Loma Linda, California.
Introduction: A growing body of evidence is building a case for the possibility of tissue regeneration within the root canal of necrotic teeth, allowing for continued root development. However, it remains unknown what type of tissue is produced after regenerative endodontics. The purpose of this study was to use blood clots and platelet-rich plasma (PRP) as scaffolds in regenerative endodontics under ideal conditions in a ferret model to examine the tissues generated within the root canals.
View Article and Find Full Text PDFGenes Dev
February 2011
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
We conducted a phenotypic, transcriptional, metabolic, and genetic analysis of quiescence in yeast induced by starvation of prototrophic cells for one of three essential nutrients (glucose, nitrogen, or phosphate) and compared those results with those obtained with cells growing slowly due to nutrient limitation. These studies address two related questions: (1) Is quiescence a state distinct from any attained during mitotic growth, and (2) does the nature of quiescence differ depending on the means by which it is induced? We found that either limitation or starvation for any of the three nutrients elicits all of the physiological properties associated with quiescence, such as enhanced cell wall integrity and resistance to heat shock and oxidative stress. Moreover, the starvations result in a common transcriptional program, which is in large part a direct extrapolation of the changes that occur during slow growth.
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