We aim to investigate the lifestyle and symptom factors related to dry eye disease (DED) presence in patients with persistent gout using the Taiwan Biobank (TWB) database. A retrospective case-control study was conducted, and patients with a history of gout longer than 10 years were enrolled in the persistent-gout group. Each persistent-gout patient was age- and sex-matched to two non-gout individuals who served as the control group, and we included a total of 973 and 1946 patients in the persistent-gout group and non-gout groups. The main outcome of our study is the presence of DED and the distribution of several lifestyle and symptom risk factors of DED in persistent-gout and non-gout individuals. Logistic regression considering the age and sex and interaction test was applied to estimate the correlation of each lifestyle and symptom risk factor to DED in the two groups. A total of 95 and 140 DED events were found in the persistent-gout and non-gout groups, with a significantly higher percentage in the persistent-gout population (aOR: 1.167, 95% CI: 1.073-3.855, = 0.0415). The visual display terminal (VDT) user ( = 0.0026) and persistent alcohol drinking ( = 0.0384) were associated with DED more often in the persistent-gout population than the non-gout population. Moreover, the percentages of DED in the patients with gout intervals of 10-20 years and more than 20 years were statistically insignificant (aOR: 1.042, 95% CI: 0.886-1.910, = 0.5279). In conclusion, VDT usage and persistent alcohol drinking are prominent lifestyle and symptom risk factors for DED occurrence in patients who have experienced gout for more than 10 years.
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http://dx.doi.org/10.3390/jcm11247378 | DOI Listing |
J Affect Disord
January 2025
Department of Epidemiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima 960-1295, Japan; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, 1 Hikariga-oka, Fukushima 960-1295, Japan. Electronic address:
Background: Few studies have prospectively, comprehensively, and by sex, examined the relationship between lifestyle and depressive symptoms. This study aimed to longitudinally examine which lifestyle factors are associated with depressive symptoms in a large cohort of Japanese participants stratified by sex.
Methods: Among 9087 office and community-based residents who attended a health measurement course at the Osaka Medical Center for Health Science and Promotion between 2001 and 2002, 6629 individuals (3962 men and 2667 women) without prior depressive symptoms were followed until the end of March 2012 to observe the associations between lifestyle factors and the development of new depressive symptoms.
World J Diabetes
January 2025
Department of Cardiology, Zhongda Hospital, Southeast University, Nanjing 210009, Jiangsu Province, China.
In this article, we discuss Ye 's recent article on the association between age at diabetes diagnosis and subsequent risk of age-related ocular diseases. The study, which utilized United Kingdom Biobank data, highlighted a strong link between early diabetes onset and major eye conditions, such as cataracts, glaucoma, age-related macular degeneration, and vision loss, independent of glycemic control and disease duration. This finding challenges the previous belief that diabetic eye disease primarily correlates with hyperglycemia.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
Faculty of Medicine, Imperial College London, London SW7 2AZ, United Kingdom.
Pediatric pancreatic tumors, though rare, pose significant diagnostic and management challenges. The recent, 22-year nationwide survey on pediatric pancreatic tumors in Japan by Makita offers valuable insights into this uncommon entity, revealing striking geographical variations and questioning current treatment paradigms. This editorial commentary analyzes the study's key findings, including the predominance of solid pseudopapillary neoplasms and their younger age of onset, which contrast sharply with Western data.
View Article and Find Full Text PDFPEC Innov
June 2025
Department of Respiratory Medicine, Royal Devon and Exeter Hospital, University of Exeter, Exeter, United Kingdom.
Objective: To assess the feasibility and acceptability of adapting a psychoeducation course (Body Reprogramming) for severe asthma and finding suggestions for improvement.
Methods: Severe asthma patients were recruited from a single centre and enrolled in an online group-based course. Each course consisted of four sessions: introduction to BR, stress, exercise, and diet.
Narra J
December 2024
Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.
Patients with generalized myasthenia gravis (MG) often show restrictive spirometry results. Although regular exercise and physical fitness are linked to better respiratory function, there is limited research assessing the effects of aerobic exercise on lung function in MG patients. The aim of this study was to analyze the effect of low-intensity aerobic exercise using a cycle ergometer on lung function parameters in MG patients.
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