AI Article Synopsis
- Paper-based biosensors are cost-effective and portable devices designed for the easy detection of biochemical substances, especially useful for point-of-care testing.
- Nucleic acid-based methods provide flexibility in detecting pathogens, and when combined with paper-based platforms, they enable accurate results in a non-laboratory setting.
- The review covers current technologies, examines challenges in integrating these systems, and suggests future research avenues to enhance paper-based biosensor development.
Article Abstract
Paper-based biosensors are microfluidic analytical devices used for the detection of biochemical substances. The unique properties of paper-based biosensors, including low cost, portability, disposability, and ease of use, make them an excellent tool for point-of-care testing. Among all analyte detection methods, nucleic acid-based pathogen detection offers versatility due to the ease of nucleic acid synthesis. In a point-of-care testing context, the combination of nucleic acid detection and a paper-based platform allows for accurate detection. This review offers an overview of contemporary paper-based biosensors for detecting nucleic acids from pathogens. The methods and limitations of implementing an integrated portable paper-based platform are discussed. The review concludes with potential directions for future research in the development of paper-based biosensors.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776365 | PMC |
| http://dx.doi.org/10.3390/bios12121094 | DOI Listing |
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