The steady state selective saturation method is a fast and efficient technique to study flow with magnetic resonance imaging. The pulse sequence used generates no signal from stationary matter and simultaneously optimizes signal flowing into a predetermined volume. The method can be used to generate three-dimensional angiography in less than 5 min. Other modifications allow the quantitative measurement of flow velocities and distinction of veins and arteries according to the direction of flow.
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http://dx.doi.org/10.1097/00004728-198709000-00025 | DOI Listing |
ACS Infect Dis
January 2025
Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454, United States.
Inosine 5'-monophosphate dehydrogenase (IMPDH) is a promising antibiotic target. This enzyme catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP), which is the rate-limiting step in guanine nucleotide biosynthesis. Bacterial IMPDH-specific inhibitors have been developed that bind to the NAD site.
View Article and Find Full Text PDFShoulder Elbow
January 2025
Department of Orthopaedics, Northwestern Medicine, Warrenville, IL, USA.
Background: The treatment algorithm for traumatic shoulder instability has evolved, emphasizing the significance of glenoid bone loss and the glenoid track, addressing humeral, and glenoid vault bone deficiencies. This study examines trends and demographics of anterior shoulder instability procedures in the United States from 2010 to 2020.
Methods: PearlDiver database was queried for patients who underwent traumatic anterior shoulder instability procedures.
JACC Adv
February 2025
Department of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Background: There continue to be significant gender disparities with women being underrepresented in medical professional society leadership roles, despite more women entering medical school.
Objectives: This study aimed to elucidate the pattern of representation of women in medical society presidential positions in the United States and Europe over the past 50 years. It further examines gender-related trends in the field of cardiology and among medical trainees.
Niger Med J
January 2025
Department of Haematology and Blood Transfusion, Rivers State University Teaching Hospital & Faculty of Basic Clinical Sciences, Rivers State University, Nigeria.
Background: Microalbuminuria, an early indicator of kidney damage in Sickle Cell Disease (SCD) patients, is linked to a heightened risk of chronic kidney disease (CKD) in adulthood. This study investigates the determinants of microalbuminuria in paediatric SCD patients in South-South Nigeria.
Methodology: This cross-sectional study was conducted over six months at the Rivers State University Teaching Hospital, Nigeria, involving 60 children with [HbSS genotype, SCD] in a steady state.
Thermal engineering can be used to exploit absorption in a silicon optical cavity. In this work, the steady state profile of the heat generated by absorption is shaped and used to generate a dynamic heterostructure in a weakly confined silicon optical cavity. This is demonstrated in an edge defect photonic crystal optomechanical cavity to produce phonon lasing and sub-GHz optical pulsing with photon-phonon cooperativity of 0.
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